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1,2-Naphthalenedione

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1,2-Naphthalenedione

EINECS 208-360-2
CAS No. 524-42-5 Density 1.29 g/cm3
PSA 34.14000 LogP 1.46520
Solubility N/A Melting Point 139-142 °C (dec.)(lit.)
Formula C10H6O2 Boiling Point 296.068 °C at 760 mmHg
Molecular Weight 158.156 Flash Point 117.376 °C
Transport Information N/A Appearance brown powder
Safety 26-36-45-36/37/39-16 Risk Codes 22-36/37/38-34-11
Molecular Structure Molecular Structure of 524-42-5 (1,2-NAPHTHOQUINONE) Hazard Symbols HarmfulXn,IrritantXi,CorrosiveC,FlammableF
Synonyms

NSC 9831;SID 8139964;o-Naphthoquinone;

Article Data 113

1,2-Naphthalenedione Chemical Properties

Chemical Name: 1,2-Naphthoquinone
IUPAC NAME: Naphthalene-1,2-dione
CAS No.: 524-42-5
EINECS: 208-360-2
RTECS: QL7000000
Molecular Formula: C10H6O2
Molecular Weight: 158.15 g/mol
Melting Point: 139-142 °C (dec.)(lit.)
Density: 1.29 g/cm3
Flash Point: 117.4 °C
Boiling Point: 296.1 °C at 760 mmHg
Storage temp.: 2-8°C
Following is the structure of 1,2-Naphthoquinone (CAS No.524-42-5):


Product Categories about 1,2-Naphthoquinone (CAS No.524-42-5) are Intermediates of Dyes and Pigments ; Anthraquinones, Hydroquinones and Quinones
The chemical synonymous of 1,2-Naphthoquinone (CAS No.524-42-5) are 1,2-Dihydro-1,2-Diketo-Naphthalene ; 1,2-Naftochinon ; 1,2-Naphthaquinone ; O-Naphthoquinone ; Naphthoquinone, 1,2- ; Beta-Naphthoquinone ; 1,2-Naphthalenedione ; 1,2-Naphthoquinone

1,2-Naphthalenedione Toxicity Data With Reference

1.    

orl-rat LDLo:250 mg/kg

    NCNSA6    National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. 5 (1953),39.
2.    

orl-mus LDLo:1070 mg/kg

    AECTCV    Archives of Environmental Contamination and Toxicology. 14 (1985),111.
3.    

orl-bwd LD50:75 mg/kg

    AECTCV    Archives of Environmental Contamination and Toxicology. 12 (1983),355.

1,2-Naphthalenedione Consensus Reports

Reported in EPA TSCA Inventory.

1,2-Naphthalenedione Safety Profile

Poison by ingestion. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Note: Irritant
Hazard Codes: HarmfulXn FlammableIrritantXi CorrosiveC
Risk Statements about 1,2-Naphthoquinone (CAS No.524-42-5):
R11:Highly flammable. 
R22:Harmful if swallowed. 
R34:Causes burns. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements about 1,2-Naphthoquinone (CAS No.524-42-5):
S16:Keep away from sources of ignition. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Attention:
1. Storage: Store in a cool, dry place. Store in a tightly closed container
2. Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.

1,2-Naphthalenedione Specification

1,2-Naphthoquinone (CAS No.524-42-5) is a polycyclic aromatic ketone. It is a reactive metabolite of naphthalene. This compound is a quinone found in diesel exhaust particles. The accumulation of this toxic metabolite in rats from doses of naphthalene has been shown to cause eye damage, including the formation of cataracts.

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