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1-METHOXY-2-FLUORENAMINE HYDRO-CHLORIDE

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1-METHOXY-2-FLUORENAMINE HYDRO-CHLORIDE

EINECS N/A
CAS No. 6893-24-9 Density N/A
PSA N/A LogP N/A
Solubility N/A Melting Point N/A
Formula C14H13NO•ClH Boiling Point 409.3°C at 760 mmHg
Molecular Weight 247.74 Flash Point 221.1°C
Transport Information N/A Appearance N/A
Safety Questionable carcinogen with experimental carcinogenic and tumorigenic data. When heated to decomposition it emits very toxic fumes of Cl and NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 6893-24-9 (1-methoxy-9H-fluoren-2-aminium chloride) Hazard Symbols N/A
Synonyms

N/A

 

1-METHOXY-2-FLUORENAMINE HYDRO-CHLORIDE Chemical Properties

Product Name:Fluphenazine(6893-24-9)
CAS No:6893-24-9
Molecular Formula:C14H14ClNO
Formula Weight:247.7201
Boiling Point:409.3 °C at 760 mmHg
Vapour Pressure:6.55E-07 mmHg at 25°C
Flash Point:221.1 °C
Synonyms of Fluphenazine(6893-24-9):(1-methoxy-9H-fluoren-2-yl)ammonium chloride;1-Methoxyfluoren-2-amine, hydrochloride;Fluoren-2-amine, 1-methoxy-, hydrochloride
Molecular Structure of Fluphenazine(6893-24-9):

1-METHOXY-2-FLUORENAMINE HYDRO-CHLORIDE Uses

Fluphenazine(6893-24-9) (marketed as Prolixin) is a typical antipsychotic drug used for the treatment of psychoses such as schizophrenia and acute manic phases of bipolar disorder.

Its main use is as a long acting injection given once every two or three weeks to people with schizophrenia who have a poor compliance with medication and suffer frequent relapses of illness.

1-METHOXY-2-FLUORENAMINE HYDRO-CHLORIDE Production

Fluphenazine decanoate Modecate, Prolixin Decanoate, Dapotum D, Anatensol, Fludecate, Sinqualone Deconoate
Fluphenazine enanthate Dapotum Injektion, Flunanthate, Moditen Enanthate Injection, Sinqualone Enanthate
Fluphenazine hydrochloride Prolixin, Permitil, Dapotum, Lyogen, Moditen, Omca, Sediten, Selecten, Sevinol, Sinqualone, Trancin

 

1-METHOXY-2-FLUORENAMINE HYDRO-CHLORIDE Toxicity Data With Reference

Its side effect profile is similar to haloperidol, namely predominantly dopamine-blocking effects which give rise to akathisia, parkinsonism and tremor. Long term side effects include the potentially irreversible tardive dyskinesia and the potentially fatal neuroleptic malignant syndrome.

1-METHOXY-2-FLUORENAMINE HYDRO-CHLORIDE Safety Profile

Notable side effects include akathisia, extrapyramidal side effects, including tardive dyskinesia and Rabbit syndrome. The frequency and severity of extrapyramidal side effects are direct proportional to the dose given and the duration of treatment.

Sedative, allergic-toxic and anticholinergic/sympatholytic side effects are less likely to occur compared with chlorpromazine. The direct deposition of fluphenazine in the cornea and retina has so far not been reported.

Neuroleptic malignant syndrome, although rare, is a potentially lethal side effect of all antipsychotics.

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