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2(1H)-Pyridinone,5-hydroxy-

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Name

2(1H)-Pyridinone,5-hydroxy-

EINECS N/A
CAS No. 5154-01-8 Density 1.379 g/cm3
PSA 53.35000 LogP 0.49280
Solubility N/A Melting Point 250-260°C
Formula C5H5NO2 Boiling Point 333.8 °C at 760 mmHg
Molecular Weight 111.1 Flash Point 155.6 °C
Transport Information N/A Appearance N/A
Safety 26-36/37 Risk Codes N/A
Molecular Structure Molecular Structure of 5154-01-8 (2,5-DIHYDROXYPYRIDINE) Hazard Symbols IrritantXi
Synonyms

2(1H)-Pyridone,5-hydroxy- (8CI);2,5-Pyridinediol (6CI,7CI);2,5-Dihydroxypyridine;5-Hydroxy-2(1H)-pyridinone;5-Hydroxy-2-pyridone;6-Hydroxy-3-pyridinol;NSC224189;

Article Data 19

2(1H)-Pyridinone,5-hydroxy- Synthetic route

C7H9NO5

5154-01-8

pyridine-2,5-diol

Conditions
ConditionsYield
With 5%-palladium/activated carbon; hydrogen In ethanol; water at 50 - 55℃; under 750.075 - 1500.15 Torr; for 4h; Autoclave;94%

C8H11NO5

5154-01-8

pyridine-2,5-diol

Conditions
ConditionsYield
With 50% Raney nickel In water; isopropyl alcohol at 60 - 65℃; under 750.075 - 1500.15 Torr; for 4h; Autoclave;93.6%

C6H7NO5

5154-01-8

pyridine-2,5-diol

Conditions
ConditionsYield
With 5%-palladium/activated carbon; hydrogen In methanol; water at 50 - 55℃; under 750.075 - 1500.15 Torr; for 4h; Autoclave;93.1%

C9H13NO5

5154-01-8

pyridine-2,5-diol

Conditions
ConditionsYield
With 50% Raney nickel In tetrahydrofuran; water at 60 - 65℃; under 750.075 - 1500.15 Torr; for 5h; Autoclave;91.5%
109-00-2

3-HYDROXYPYRIDINE

5154-01-8

pyridine-2,5-diol

Conditions
ConditionsYield
With sodium hydroxide; water
With sodium hydroxide; water at 300 - 310℃;
98-01-1

furfural

A

109-00-2

3-HYDROXYPYRIDINE

B

5154-01-8

pyridine-2,5-diol

Conditions
ConditionsYield
With ethanol; water; hydrazinium sulfate at 153℃; unter Druck;
142-08-5

2-hydroxypyridin

5154-01-8

pyridine-2,5-diol

Conditions
ConditionsYield
With sodium hydroxide; dipotassium peroxodisulfate; iron(II) sulfate Erwaermen des mit Schwefelsaeure angesaeuerten Reaktionsgemisches auf 100grad.;
51834-97-0

6-methoxypyridine-3-ol

5154-01-8

pyridine-2,5-diol

Conditions
ConditionsYield
With hydrogen bromide
99970-14-6

5-benzoyloxy-pyridin-2-ol

5154-01-8

pyridine-2,5-diol

Conditions
ConditionsYield
With hydrogen bromide
408338-50-1

2,5-diethoxy-pyridine

5154-01-8

pyridine-2,5-diol

Conditions
ConditionsYield
With hydrogen bromide

2(1H)-Pyridinone,5-hydroxy- Specification

The 2(1H)-Pyridinone,5-hydroxy-, with the CAS registry number 5154-01-8, has the systematic name of 5-hydroxypyridin-2(1H)-one. It belongs to the following product categories: Pharmacetical; Pyridine series; Pyridine; Pyridines. And the molecular formula of the chemical is C5H5NO2. What's more, while dealing with it, you had better take the following instructions: Wear suitable protective clothing and gloves, and if in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

The characteristics of 2(1H)-Pyridinone,5-hydroxy- are as followings: (1)ACD/LogP: -0.82; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.82; (4)ACD/LogD (pH 7.4): -0.86; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 8.56; (8)ACD/KOC (pH 7.4): 7.72; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 29.54 Å2; (13)Index of Refraction: 1.593; (14)Molar Refractivity: 27.33 cm3; (15)Molar Volume: 80.5 cm3; (16)Polarizability: 10.83×10-24cm3; (17)Surface Tension: 58.2 dyne/cm; (18)Density: 1.379 g/cm3; (19)Flash Point: 155.6 °C; (20)Enthalpy of Vaporization: 66.81 kJ/mol; (21)Boiling Point: 333.8 °C at 760 mmHg; (22)Vapour Pressure: 9.49E-06 mmHg at 25°C.

Addtionally, the following datas could be converted into the molecular structure:
(1)SMILES: O=C1/C=C\C(\O)=C/N1
(2)InChI: InChI=1/C5H5NO2/c7-4-1-2-5(8)6-3-4/h1-3,7H,(H,6,8)
(3)InChIKey: CHGPEDOMXOLANF-UHFFFAOYAE

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