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2,5-DICHLORO-4-NITROANILINE

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Name

2,5-DICHLORO-4-NITROANILINE

EINECS 229-591-5
CAS No. 6627-34-5 Density 1.624g/cm3
PSA 71.84000 LogP 3.58820
Solubility N/A Melting Point 150-155 ºC
Formula C6H4 Cl2 N2 O2 Boiling Point 361.1°C at 760 mmHg
Molecular Weight 207.016 Flash Point 172.2°C
Transport Information N/A Appearance yellow powder
Safety Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx and Cl. Risk Codes R36/37/38   
Molecular Structure Molecular Structure of 6627-34-5 (2,5-DICHLORO-4-NITROANILINE) Hazard Symbols
Synonyms

Aniline,2,5-dichloro-4-nitro- (7CI,8CI); 2,5-Dichloro-4-nitroaniline;2,5-Dichloro-4-nitrophenylamine; NSC 60645

Article Data 9

2,5-DICHLORO-4-NITROANILINE Synthetic route

17488-25-4

1,4-dichloro-2,5-dinitrobenzene

6627-34-5

2,5-dichloro-4-nitroaniline

Conditions
ConditionsYield
With ammonia
17488-25-4

1,4-dichloro-2,5-dinitrobenzene

A

6627-34-5

2,5-dichloro-4-nitroaniline

B

67382-07-4

2,5-dinitro-p-phenylenediamine

Conditions
ConditionsYield
With ethanol; ammonia
2621-62-7

2,5-dichloroacetanilide

6627-34-5

2,5-dichloro-4-nitroaniline

Conditions
ConditionsYield
With sulfuric acid; nitric acid at 5 - 10℃; folgendes Verseifen mit verd.Natronlauge;
With nitrating mixture; sulfuric acid at 45℃; das Acetylderivat entsteht;
Multi-step reaction with 2 steps
1: nitration
2: hydrolysis
View Scheme
2621-62-7

2,5-dichloroacetanilide

A

6627-34-5

2,5-dichloro-4-nitroaniline

B

38411-18-6

acetic acid-(3,6-dichloro-2-nitro-anilide)

Conditions
ConditionsYield
With nitric acid man extrahiert das 2.5-Dichlor-4-nitro-acetanilid durch Auskochen mit Benzol; die Benzolloesung dampft man ein und zersetzt das asgeschiedene Acetylderivat durch Erhitzen mit waessr.Ammoniak auf 180grad;
38411-17-5

2,5-dchloro-4-nitroacetanilide

6627-34-5

2,5-dichloro-4-nitroaniline

Conditions
ConditionsYield
With sulfuric acid at 100 - 110℃;
hydrolysis;
17488-25-4

1,4-dichloro-2,5-dinitrobenzene

7664-41-7

ammonia

6627-34-5

2,5-dichloro-4-nitroaniline

17488-25-4

1,4-dichloro-2,5-dinitrobenzene

7664-41-7

ammonia

A

6627-34-5

2,5-dichloro-4-nitroaniline

B

67382-07-4

2,5-dinitro-p-phenylenediamine

2621-62-7

2,5-dichloroacetanilide

HNO3+H2SO4

HNO3+H2SO4

6627-34-5

2,5-dichloro-4-nitroaniline

Conditions
ConditionsYield
und Verseifen mit Natronlauge;
106-46-7

para-dichlorobenzene

6627-34-5

2,5-dichloro-4-nitroaniline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: HNO3+H2SO4
2: alcoholic ammonia
View Scheme
Multi-step reaction with 2 steps
1: HNO3+H2SO4
2: alcohol; ammonia
View Scheme
6627-34-5

2,5-dichloro-4-nitroaniline

130-15-4

[1,4]naphthoquinone

20103-09-7

2,5-dichloro-1,4-phenylenediamine

Conditions
ConditionsYield
With sodium hydroxide; hydrazine hydrate In water96%
With sodium hydroxide; hydrazine hydrate In water91%

2,5-DICHLORO-4-NITROANILINE Chemical Properties

Empirical Formula: C6H4Cl2N2O
Molecular Weight: 207.0142 
IUPAC Name: 2,5-Dichloro-4-nitroaniline
Synonyms: 2,5-Dichloro-4-nitro-anilin ; Benzenamine,2,5-dichloro-4-nitro- ; 2,5-Dichloro-4-nitrobenzenamine ; Aniline, 2,5-dichloro-4-nitro-
Melting Point: 154-158 °C(lit.)
Flash Point of 2,5-Dichloro-4-nitroaniline (6627-34-5): 172.2 °
Boiling Point: 361.1 °C at 760 mmHg
Density of 2,5-Dichloro-4-nitroaniline (6627-34-5): 1.624 g/cm3 
Vapour Pressure: 2.12E-05 mmHg at 25°C
Index of Refraction: 1.655  
Physical State: 2,5-Dichloro-4-nitroaniline (6627-34-5) is a yellow powder

2,5-DICHLORO-4-NITROANILINE Toxicity Data With Reference

1.    

orl-rat LD50:2820 mg/kg

    85JCAE    Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,599.

2,5-DICHLORO-4-NITROANILINE Consensus Reports

Reported in EPA TSCA Inventory.

2,5-DICHLORO-4-NITROANILINE Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx and Cl.
Safety: WARNING: Irritates lungs, eyes, skin
Hazard Codes: Xi: Irritant
Risk Statements: 36/37/38: Irritating to eyes, respiratory system and skin 
Safety Statements: 26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
37/39: Wear suitable gloves and eye/face protection
RIDADR: 2811
WGK Germany: 3
RTECS: BX2950000

2,5-DICHLORO-4-NITROANILINE Specification

 2,5-Dichloro-4-nitroaniline (6627-34-5) is a yellow powder, which should store in a cool, dry place with a tightly closed container.

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