Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
2,5-Dichloropyrimidine |
EINECS | 639-415-2 |
CAS No. | 22536-67-0 | Density | 1.493 g/cm3 |
PSA | 25.78000 | LogP | 1.78340 |
Solubility | Slightly soluble in water. | Melting Point |
57.0-57.5 °C |
Formula | C4H2Cl2N2 | Boiling Point | 265.3 °C at 760 mmHg |
Molecular Weight | 148.979 | Flash Point | 139.8 °C |
Transport Information | N/A | Appearance | N/A |
Safety | 26-39-61 | Risk Codes | 22-41-50 |
Molecular Structure | Hazard Symbols | C | |
Synonyms |
2,5-Dichlorpyrimidin; |
Article Data | 15 |
(2-chloropyrimidin-5-yl)boronic acid
2,5-dichloropyrimidine
Conditions | Yield |
---|---|
With N-chloro-succinimide; copper(l) chloride In acetonitrile at 80℃; for 16h; | 75% |
5-chloropyrimidin-2-amine
2,5-dichloropyrimidine
Conditions | Yield |
---|---|
With hydrogenchloride; sodium nitrite |
5-chloropyrimidin-2-one
2,5-dichloropyrimidine
Conditions | Yield |
---|---|
With trichlorophosphate |
2-hydroxypyrimidine hydrochloride
2,5-dichloropyrimidine
Conditions | Yield |
---|---|
With chlorine; N,N-dimethyl-aniline; trichlorophosphate Yield given. Multistep reaction; |
2-hydroxy-5-chloropyrimidine
2,5-dichloropyrimidine
Conditions | Yield |
---|---|
Stage #1: 5-chloro-2-hydroxypyrimidine With N,N-dimethyl-aniline; trichlorophosphate at 120℃; for 1h; Stage #2: With water at 0℃; | |
Stage #1: 5-chloro-2-hydroxypyrimidine With N,N-dimethyl-aniline; trichlorophosphate at 120℃; for 1h; Stage #2: With water | |
With trichlorophosphate In N,N-dimethyl-aniline at 120℃; for 1h; Inert atmosphere; | 6 g |
2,4,5-trichloropyrimidine
2,5-dichloropyrimidine
Conditions | Yield |
---|---|
Stage #1: 2,4,5-trichloropyrimidine With hydrogen; palladium 10% on activated carbon In methanol at 50℃; for 2h; Stage #2: With sodium hydrogencarbonate In methanol; water at 20℃; | |
With acetic acid; zinc In tetrahydrofuran at 20℃; for 2h; Heating; Reflux; | |
With acetic acid; zinc In tetrahydrofuran for 2h; Reflux; | |
Stage #1: 2,4,5-trichloropyrimidine With acetic acid; zinc In tetrahydrofuran for 2h; Reflux; Stage #2: With sodium hydrogencarbonate; sodium hydroxide In dichloromethane; water pH=10; | |
With acetic acid; zinc In tetrahydrofuran at 20℃; Reflux; |
2,5-dichloropyrimidine
(5-Chloro-pyrimidin-2-yl)-cyano-acetic acid ethyl ester
Conditions | Yield |
---|---|
at 70℃; for 3h; | 100% |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol Reflux; | 100% |
2,5-dichloropyrimidine
Conditions | Yield |
---|---|
With triethylamine In isopropyl alcohol at 80℃; for 3h; | 97% |
2,5-dichloropyrimidine
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 1h; | 97% |