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Name |
2-Amino-6-chlorobenzoic acid |
EINECS | 218-416-8 |
CAS No. | 2148-56-3 | Density | 1.476 g/cm3 |
PSA | 63.32000 | LogP | 2.20160 |
Solubility | Very soluble in water. Soluble in methanol. | Melting Point |
158-160 °C(lit.) |
Formula | C7H6ClNO2 | Boiling Point | 339.3 °C at 760 mmHg |
Molecular Weight | 171.583 | Flash Point | 159 °C |
Transport Information | N/A | Appearance | white to light yellow crystal powder |
Safety | 26-36-37/39 | Risk Codes | 36/37/38 |
Molecular Structure | Hazard Symbols | Xi | |
Synonyms |
Anthranilicacid, 6-chloro- (6CI,7CI,8CI);6-Chloroanthranilic acid; |
Article Data | 17 |
Conditions | Yield |
---|---|
With potassium bisulfite; cerium(III) chloride; potassium chloride; 2-methoxy-phenol In ethanol at 65℃; for 8h; Time; | 90% |
With platinum Hydrogenation; | |
With ammonium hydroxide; iron(II) sulfate | |
With iron(II) sulfate |
2-[(tert-butoxycarbonyl)amino]-6-chlorobenzoic acid
2-chloro-6-aminobenzoic acid
Conditions | Yield |
---|---|
With hydrogenchloride In 1,4-dioxane; water at 90℃; under 760.051 Torr; for 1h; Temperature; | 99.5% |
Conditions | Yield |
---|---|
With dihydrogen peroxide; potassium hydroxide Reflux; | 94% |
With dihydrogen peroxide; potassium hydroxide In water for 12h; Reflux; | 94% |
2-(acetylamino)-6-chlorobenzoic acid
2-chloro-6-aminobenzoic acid
Conditions | Yield |
---|---|
With hydrogenchloride | |
With hydrogenchloride Zers. des entstandenen Hydrochlorids mit Natriumdicarbonat; | |
With hydrogenchloride at 80 - 90℃; for 1.5h; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 65.7 percent / potassium permanganate; magnesium sulfate heptahydrate / H2O / 5 h / 135 - 160 °C 2: hydrochloric acid / 1.5 h / 80 - 90 °C View Scheme | |
Multi-step reaction with 2 steps 1: potassium permanganate; magnesium sulfate 2: concentrated hydrochloric acid / Zers. des entstandenen Hydrochlorids mit Natriumdicarbonat View Scheme | |
Multi-step reaction with 2 steps 1: potassium permanganate; magnesium sulfate; water 2: aqueous hydrochloric acid View Scheme |
Conditions | Yield |
---|---|
With sodium hydroxide; dihydrogen peroxide |
2-benzoylamino-6-chloro-benzoic acid
2-chloro-6-aminobenzoic acid
Conditions | Yield |
---|---|
With sodium hydroxide |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: sodium acetate 2: potassium permanganate; magnesium sulfate; water 3: aqueous hydrochloric acid View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 90.2 percent / CH2Cl2 2: 65.7 percent / potassium permanganate; magnesium sulfate heptahydrate / H2O / 5 h / 135 - 160 °C 3: hydrochloric acid / 1.5 h / 80 - 90 °C View Scheme | |
Multi-step reaction with 3 steps 1: fluorobenzene / 2 h / 50 °C 2: water / tetrahydrofuran / 9.17 h / 155 - 175 °C / 5320.36 - 7600.51 Torr / Inert atmosphere 3: hydrogenchloride / 1,4-dioxane; water / 1 h / 90 °C / 760.05 Torr View Scheme |
Conditions | Yield |
---|---|
With D-glucose; Escherichia coli flavin reductase; Bacillus megaterium glucose dehydrogenase; Lechevalieria aerocolonigenes tryptophan-7-halogenase; flavin adenine dinucleotide; NADH; sodium chloride In aq. phosphate buffer; isopropyl alcohol pH=7.4; Enzymatic reaction; |
IUPAC Name: 2-amino-6-chlorobenzoic acid
Empirical Formula: C7H6ClNO2
Molecular Weight: 171.581g/mol
EINECS: 218-416-8
Structure of 2-Amino-6-chlorobenzoic acid (CAS NO.2148-56-3):
Index of Refraction: 1.648
Molar Refractivity: 42.31 cm3
Molar Volume: 116.1 cm3
Polarizability: 16.77×10-24cm3
Surface Tension: 65.9 dyne/cm
Density: 1.476 g/cm3
Flash Point: 159 °C
Enthalpy of Vaporization: 61.5 kJ/mol
Melting Point: 158-160 °C(lit.)
Boiling Point: 339.3 °C at 760 mmHg
Vapour Pressure: 3.61E-05 mmHg at 25°C
Physical Appearance: white to light yellow crystal powder
Product Categories: benzene derivative;Amino Acids and Derivatives;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Organic acids
Canonical SMILES: C1=CC(=C(C(=C1)Cl)C(=O)O)N
InChI: InChI=1S/C7H6ClNO2/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,9H2,(H,10,11)
InChIKey: SZCPTRGBOVXVCA-UHFFFAOYSA-N
2-Amino-6-chlorobenzoic acid (2148-56-3)is used as intermediate for medicine and pesticides.
Hazard Codes: Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany: 3
Hazard Note: Irritant
First Aid Measures of 2-Amino-6-chlorobenzoic acid (2148-56-3):
Ingestion:Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin:Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes:Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Storage of 2-Amino-6-chlorobenzoic acid (2148-56-3):
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.