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2-Hydroxy-6-aminopurine

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Name

2-Hydroxy-6-aminopurine

EINECS 222-157-6
CAS No. 3373-53-3 Density 2.19 g/cm3
PSA 100.71000 LogP 0.22190
Solubility slightly soluble in water Melting Point 300 °C
Formula C5H5N5O Boiling Point 273.11°C (rough estimate)
Molecular Weight 151.128 Flash Point N/A
Transport Information N/A Appearance white to light yellow crystal powder
Safety 24/25 Risk Codes 22
Molecular Structure Molecular Structure of 3373-53-3 (6-Amino-3,7-dihydro-2H-purin-2-one) Hazard Symbols Xn
Synonyms

2H-Purin-2-one,6-amino-1,3-dihydro- (9CI);Isoguanine (6CI,7CI,8CI);2-Hydroxyadenine;2-Oxoadenine;2-Oxyadenine;6-Amino-2-hydroxypurine;Guanopterin;NSC 241501;

Article Data 24

2-Hydroxy-6-aminopurine Synthetic route

1198-83-0

2-(methylthio)-7H-purin-6-amine

3373-53-3

isoguanine

Conditions
ConditionsYield
With ethanol; dihydrogen peroxide
Multi-step reaction with 2 steps
1: chlorine; H2O
2: aq. NaOH solution
View Scheme
22715-34-0

4,5,6-triamino-1H-pyrimidin-2-one

3373-53-3

isoguanine

Conditions
ConditionsYield
With formic acid at 160℃;
7357-53-1

2-methanesulfonyl-7(9)H-purin-6-ylamine

3373-53-3

isoguanine

Conditions
ConditionsYield
With sodium hydroxide
1839-18-5

6-Amino-2-chlorpurin

3373-53-3

isoguanine

Conditions
ConditionsYield
With hydrogenchloride
5-amino-1(3)H-imidazole-4-carboxamidine dihydrochloride

5-amino-1(3)H-imidazole-4-carboxamidine dihydrochloride

3373-53-3

isoguanine

Conditions
ConditionsYield
With urea at 180℃;
With sodium hydroxide
8-chloro-2-ethoxy-6-amino-purine

8-chloro-2-ethoxy-6-amino-purine

3373-53-3

isoguanine

Conditions
ConditionsYield
With phosphonium iodide; hydrogen iodide at 30 - 40℃;
crotonoside

crotonoside

3373-53-3

isoguanine

Conditions
ConditionsYield
With sulfuric acid Hydrogenation;
2914-09-2

2,8-dichloro-7(9)H-purin-6-ylamine

3373-53-3

isoguanine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: palladium/BaSO4; aq. NaOH solution
2: aqueous HCl
View Scheme
3373-53-3

isoguanine

69-89-6

xanthin

Conditions
ConditionsYield
With genes from Klebsiella pneumoniae subsp. pneumoniae In aq. buffer at 30℃; pH=7.5; Kinetics; Temperature; Reagent/catalyst; Enzymatic reaction;
3373-53-3

isoguanine

6-amino-2-oxo-1H,7H-purin-3-ium chloride

Conditions
ConditionsYield
With hydrogenchloride In water

2-Hydroxy-6-aminopurine Chemical Properties

IUPAC Name: 6-Amino-1,7-dihydropurin-2-one
CAS: 3373-53-3
Formula: C5H5N5O
Molecular Structure of 6-Amino-1,7-dihydropurin-2-one (3373-53-3):
      
Molecular Weight: 151.13
Melting Point: 300 °C 
Water Solubility: 1e+006(mg/L) at 25°C
Index of Refraction: 2.047 
Molar Refractivity: 35.46 cm3 
Molar Volume: 68.8 cm
Polarizability: 14.06 10-24cm3
Surface Tension: 124 dyne/cm 
Density: 2.19 g/cm3 
Appearance: white to light yellow crystal powder   
The classification of 6-Amino-1,7-dihydropurin-2-one (3373-53-3) are purine;nucleotides and nucleosides;purines;biochemistry;nucleobases and their analogs;nucleosides, nucleotides & related
reagents;nucleic acids;bases & related reagents;intermediates & fine chemicals;nucleotides;pharmaceuticals.

2-Hydroxy-6-aminopurine Safety Profile

Safety statements about 6-Amino-1,7-dihydropurin-2-one (3373-53-3):
S24/25: Avoid contact with skin and eyes. 

2-Hydroxy-6-aminopurine Specification

  The chemical synonyms of 6-Amino-1,7-dihydropurin-2-one (3373-53-3) are 2-Hydroxy-6-aminopurine ; 6-Amino-1,3-dihydro-2h-purin-2-one ; Isoguanine ; 6-Amino-3,7-dihydro-2h-purin-2-one ; 6-Amino-1,7-dihydropurin-2-one .
 The product of 6-Amino-1,7-dihydropurin-2-one (3373-53-3) can be used a nucleotide base as immunostimulator agent.
 Handling and Storage of 6-amino-1,7-dihydropurin-2-one (3373-53-3): Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Store in a cool, dry place. Store in a tightly closed container. Personal protective equipment: Wear chemical splash goggles.Wear appropriate protective gloves to prevent skin exposure and wear appropriate protective clothing to prevent skin exposure. Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. 

 

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