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Name |
2-Hydroxyphenylacetic acid |
EINECS | 210-393-2 |
CAS No. | 614-75-5 | Density | 1.319 g/cm3 |
PSA | 57.53000 | LogP | 1.01930 |
Solubility | Soluble in Methanol and Water. | Melting Point |
145-147 °C(lit.) |
Formula | C8H8O3 | Boiling Point | 328.1 °C at 760 mmHg |
Molecular Weight | 152.15 | Flash Point | 166.5 °C |
Transport Information | N/A | Appearance | off-white solid |
Safety | 26-36 | Risk Codes | 36/37/38 |
Molecular Structure | Hazard Symbols | Xi | |
Synonyms |
Aceticacid, (o-hydroxyphenyl)- (8CI);(2-Hydroxyphenyl)acetic acid;(o-Hydroxyphenyl)acetic acid;2-HPAA;Benzeneaceticacid, 2-hydroxy-;NSC 62000; |
Article Data | 67 |
Molecule structure of 2-Hydroxyphenylacetic acid (CAS NO.614-75-5):
IUPAC Name: 2-(2-Hydroxyphenyl)acetic acid
Molecular Weight: 152.14732 g/mol
Molecular Formula: C8H8O3
Density: 1.321 g/cm3
Melting Point: 145-147 °C(lit.)
Boiling Point: 321.8 °C at 760 mmHg
Flash Point: 162.6 °C
Index of Refraction: 1.59
Molar Refractivity: 38.9 cm3
Molar Volume: 115.1 cm3
Polarizability: 15.42×10-24 cm3
Surface Tension: 60.4 dyne/cm
Enthalpy of Vaporization: 59.5 kJ/mol
Vapour Pressure: 0.00012 mmHg at 25 °C
Water Solubility: 1.32E+05 mg/L
XLogP3: 0.9
H-Bond Donor: 2
H-Bond Acceptor: 3
Rotatable Bond Count: 2
Tautomer Count: 3
Exact Mass: 152.047344
MonoIsotopic Mass: 152.047344
Topological Polar Surface Area: 57.5
Heavy Atom Count: 11
Complexity: 144
Canonical SMILES: C1=CC=C(C(=C1)CC(=O)O)O
InChI: InChI=1S/C8H8O3/c9-7-4-2-1-3-6(7)5-8(10)11/h1-4,9H,5H2,(H,10,11)
InChIKey: CCVYRRGZDBSHFU-UHFFFAOYSA-N
EINECS: 210-393-2
Product Categories: FINE Chemical & INTERMEDIATES; Aromatic Phenylacetic Acids and Derivatives; Aromatics; C8; Carbonyl Compounds; Carboxylic Acids
2-Hydroxyphenylacetic acid (CAS NO.614-75-5) is used as an important intermediate in pharmaceutical synthesis.
2-Chloro acetic acid reacts with 8-hydroxyquinoline copper (Ⅱ) at the presence of sodium hydroxide, reaction temperature 170 °C, pressure of 650 ~ 700kPa, can get the product.
Hazard Codes: Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
WGK Germany: 3
F: 10-23
Hazard Note: Irritant
HS Code: 29182990
2-Hydroxyphenylacetic acid (CAS NO.614-75-5) is also named as (2-Hydroxyphenyl)acetic acid ; 2-Hydroxybenzeneacetic acid ; 2-Hydroxyphenylacetate ; 2-Hydroxyphenylacetic acid ; Hydroxyphenylacetic acid ; NSC 62000 ; o-Hydroxy phenylacetic acid ; o-Hydroxyphenylacetic acid . 2-Hydroxyphenylacetic acid (CAS NO.614-75-5) is off-white solid. It insoluble in water, soluble in benzene, toluene and other organic solvents.