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Name	2-Isopropyl-6-methylpyrimidin-4-ol	EINECS	220-561-7
CAS No.	2814-20-2	Density	1.11g/cm³
PSA	46.01000	LogP	1.61400
Solubility	N/A	Melting Point	172-175 °C(lit.)
Formula	C8H12 N2 O	Boiling Point	230.5°Cat760mmHg
Molecular Weight	152.196	Flash Point	93.2°C
Transport Information	N/A	Appearance	BEIGE NEEDLES
Safety	Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NO_x.	Risk Codes	R36/37/38
Molecular Structure		Hazard Symbols
Synonyms	4(1H)-Pyrimidinone,2-isopropyl-6-methyl- (8CI); 4(1H)-Pyrimidinone, 6-methyl-2-(1-methylethyl)-(9CI); 4-Pyrimidinol, 2-isopropyl-6-methyl- (6CI,7CI);2-Isopropyl-4-methyl-6-hydroxypyrimidine; 2-Isopropyl-4-methyl-6-pyrimidinone;2-Isopropyl-4-methylpyrimidin-6-ol; 2-Isopropyl-6-methyl-4(3H)-pyrimidone;2-Isopropyl-6-methyl-4-hydroxypyrimidine; 2-Isopropyl-6-methyl-4-pyrimidinol;2-Isopropyl-6-methyl-4-pyrimidone; 4-Hydroxy-2-isopropyl-6-methylpyrimidine; G27550; IMHP; Pyrimidinol	Article Data	22

2-Isopropyl-6-methylpyrimidin-4-ol Chemical Properties

IUPAC Name: 2-Isopropyl-6-methyl-4-hydroxypyrimidine
The MF of 2-Isopropyl-6-methyl-4-hydroxypyrimidine (2814-20-2) is C₈H₁₂N₂O.

The MW of 2-Isopropyl-6-methyl-4-hydroxypyrimidine (2814-20-2) is 152.19.
Synonyms of 2-Isopropyl-6-methyl-4-hydroxypyrimidine (2814-20-2): 2-Isopropyl-6-methylpyrimidin-4(1H)-one ; 6-Methyl-2-(1-methylethyl)pyrimidin-4(1H)-one ; Pyrimidinol ; 2-Isopropyl-4-hydroxy-6-methylpyrimidine
Product Categories: Heterocyclic Compounds;Pyrimidines;Building Blocks;Heterocyclic Building Blocks;Alpha sort;Alphabetic;H-MAnalytical Standards;IEnvironmental Standards;Metabolites;Pesticides&Metabolites
Index of Refraction: 1.545
Form: beige needles
EINECS: 220-561-7
Density: 1.11 g/ml
Flash Point: 93.2 °C
Boiling Point: 230.5 °C
Melting Point: 172-175 °C

2-Isopropyl-6-methylpyrimidin-4-ol Uses

2-Isopropyl-6-methyl-4-hydroxypyrimidine (2814-20-2) is used as rganophosphorus pesticide diazinon, pharmaceutical intermediates.

2-Isopropyl-6-methylpyrimidin-4-ol Production

Its preparation is obtained by the different isobutyraldehyde nitrile with methanol and hydrogen chloride reaction, made imine ether hydrochloride. Reaction equation is as follows:
By the imine ether hydrochloride with ammonia to produce iso-Spd, and then with ethyl acetoacetate in the presence of sodium hydroxide, forming the ring 2 - isopropyl -4 - methyl -6 - hydroxypyrimidine .

2-Isopropyl-6-methylpyrimidin-4-ol Toxicity Data With Reference

1.		orl-rat LD50:2700 mg/kg		JAFCAU Journal of Agricultural and Food Chemistry. 18 (1970),208.
2.		orl-mus LD50:2200 mg/kg		GISAAA Gigiena i Sanitariya. 52 (3)(1987),69.

2-Isopropyl-6-methylpyrimidin-4-ol Consensus Reports

Reported in EPA TSCA Inventory.

2-Isopropyl-6-methylpyrimidin-4-ol Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NO_x.
Safety information of 2-Isopropyl-6-methyl-4-hydroxypyrimidine (2814-20-2):
Hazard Codes Xi
Risk Statements
36/37/38 Irritating to eyes, respiratory system and skin
Safety Statements
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
37/39 Wear suitable gloves and eye/face protection
WGK Germany 2
RTECS UW7525000

2-Isopropyl-6-methylpyrimidin-4-ol Specification

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.Store in a cool, dry place. Keep container closed when not in use.

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