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Name	2-Methylindole-3-acetic acid	EINECS	-0
CAS No.	1912-43-2	Density	1.3 g/cm³
PSA	53.09000	LogP	2.10340
Solubility	N/A	Melting Point	205 °C (dec.)(lit.)
Formula	C₁₁H₁₁NO₂	Boiling Point	418.158 °C at 760 mmHg
Molecular Weight	189.214	Flash Point	206.695 °C
Transport Information	N/A	Appearance	N/A
Safety	22-24/25	Risk Codes	N/A
Molecular Structure		Hazard Symbols	Xi
Synonyms	(2-Methyl-1H-indol-3-yl)acetic acid;Indole-3-aceticacid, 2-methyl- (6CI,7CI,8CI);2-(2-Methyl-1H-indol-3-yl)acetic acid;2-Methyl-1H-indole-3-acetic acid;2-Methyl-3-indolylacetic acid;	Article Data	28

2-Methylindole-3-acetic acid Synthetic route

: 588-60-3
Levulinic acid phenylhydrazone

: 1912-43-2
2-methyl-3-indoleacetic acid

Conditions

Conditions	Yield
With hydrogenchloride; acetic acid for 4h; Heating;	87%
With zinc(II) chloride at 125℃;
With methanol; sulfuric acid

: 123-76-2
levulinic acid

: 100-63-0
phenylhydrazine

: 1912-43-2
2-methyl-3-indoleacetic acid

Conditions

Conditions	Yield
With acetic acid for 4h; Reflux;	78%

: 623-73-4
diazoacetic acid ethyl ester

: 95-20-5
2-methyl-1H-indole

: 1912-43-2
2-methyl-3-indoleacetic acid

Conditions

Conditions	Yield
at 200℃; Verseifen des entstandenen Aethylesters mit Kalilauge;

: 95-20-5
2-methyl-1H-indole

: 50-00-0
formaldehyd

: 1912-43-2
2-methyl-3-indoleacetic acid

Conditions

Conditions	Yield
With potassium cyanide; ethanol
With potassium cyanide; ethanol

: 21909-49-9
ethyl (2-methylindol-3-yl)acetate

: 1912-43-2
2-methyl-3-indoleacetic acid

Conditions

Conditions	Yield
With potassium hydroxide
With water; sodium hydroxide for 21h; Reflux;	2.74 g

: 4071-16-3
2-(2-methyl-1H-indol-3-yl)acetonitrile

: 1912-43-2
2-methyl-3-indoleacetic acid

Conditions

Conditions	Yield
With potassium hydroxide

: 37125-92-1
2-methylgramine

: 143-33-9
sodium cyanide

: 1912-43-2
2-methyl-3-indoleacetic acid

Conditions

Conditions	Yield
With ethanol

: 4,4'-(2,3-diphenyl-tetrazanediylidene)-di-valeric acid bis-(N'-phenyl-hydrazide)

: 1912-43-2
2-methyl-3-indoleacetic acid

Conditions

Conditions	Yield
With hydrogenchloride; ethanol

: 3397-38-4
Ethyl 4-Phenylhydrazonopentanoate

: 1912-43-2
2-methyl-3-indoleacetic acid

Conditions

Conditions	Yield
With zinc(II) chloride at 140℃; Behandeln des entstandenen Aethylesters mit alkoh. Kalilauge;
With boron trifluoride diethyl etherate at 125℃; Erwaermen des Reaktionsprodukts mit wss. NaOH;

: 5416-80-8
2-methyl-1H-indole-3-carbaldehyde

: 33577-16-1
methyl methylsulfinylmethyl sulfide

: 1912-43-2
2-methyl-3-indoleacetic acid

Conditions

Conditions	Yield
With hydrogenchloride; N-benzyl-trimethylammonium hydroxide 1.) THF, reflux, 10 h, 2.) aq. ethanol, room temp., 1 h; Multistep reaction;

2-Methylindole-3-acetic acid Chemical Properties

IUPAC Name: 2-(2-Methyl-1H-indol-3-yl)acetic acid
Product Name: 2-Methylindole-3-acetic acid
The MF of 2-(2-Methyl-1H-indol-3-yl)acetic acid (CAS NO.1912-43-2) is C₁₁H₁₁NO₂.

The MW of 2-(2-Methyl-1H-indol-3-yl)acetic acid (CAS NO.1912-43-2) is 189.21.
Synonyms of 2-(2-Methyl-1H-indol-3-yl)acetic acid (CAS NO.1912-43-2): (2-Methyl-1H-indol-3-yl)acetic acid ; 1H-Indole-3-acetic acid, 2-methyl- ; 2-Methyl-3-indoleacetic acid ; 2-Methylindole-3-Acetic Acid ; (2-Methyl-1H-indol-3-yl)-acetic acid
Product Categories: Indoles and derivatives;Imidazol&Benzimidazole;Building Blocks;Heterocyclic Building Blocks;Indoles
Index of Refraction: 1.671
Density: 1.299 g/ml
Flash Point: 206.7 °C
Boiling Point: 418.2 °C
Melting Point: 198-204 °C
BRN: 152701

2-Methylindole-3-acetic acid Uses

2-(2-Methyl-1H-indol-3-yl)acetic acid (CAS NO.1912-43-2) is used as chemical synthesis, fine chemicals, pharmaceutical intermediates.

2-Methylindole-3-acetic acid Safety Profile

Safety information of 2-(2-Methyl-1H-indol-3-yl)acetic acid (CAS NO.1912-43-2):
Hazard Codes Irritant Xi
Safety Statements
22 Do not breathe dust
24/25 Avoid contact with skin and eyes
WGK Germany 3

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