Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
3'-Aminoacetophenone |
EINECS | 202-722-3 |
CAS No. | 99-03-6 | Density | 1.096 g/cm3 |
PSA | 43.09000 | LogP | 2.05260 |
Solubility | 7.056g/L(37.5 oC) | Melting Point |
94-98 °C(lit.) |
Formula | C8H9NO | Boiling Point | 290.3 °C at 760 mmHg |
Molecular Weight | 135.166 | Flash Point | 129.4 °C |
Transport Information | N/A | Appearance | yellow to light brown crystalline powder |
Safety | 36/37-36-26 | Risk Codes | 22-36/37/38 |
Molecular Structure | Hazard Symbols | Xn,Xi | |
Synonyms |
Acetophenone,3'-amino- (8CI);1-(3-Aminophenyl)ethanone;1-Acetyl-3-aminobenzene;3-Acetylaniline;3-Acetylphenylamine;3-Methylcarbonylaniline;NSC 7637;m-Acetylaniline;m-Aminoacetophenone;b-Aminoacetophenone;3-Aminoacetophenone; |
Article Data | 158 |
Conditions | Yield |
---|---|
With cadmium sulphide; ammonium formate In water at 20℃; for 14h; Inert atmosphere; Irradiation; Sealed tube; chemoselective reaction; | 100% |
With water; oxalic acid; titanium(IV) oxide for 3h; Wavelength; Irradiation; Inert atmosphere; Sealed tube; Green chemistry; chemoselective reaction; | 100% |
With hydrogen In methanol at 70℃; under 3750.38 - 7500.75 Torr; for 4h; Temperature; Reagent/catalyst; Solvent; | 99% |
3-acetylenephenylamine
1-(3-aminophenyl)ethanone
Conditions | Yield |
---|---|
With silver hexafluoroantimonate In methanol; water at 120℃; for 24h; Sealed tube; | 97% |
With C22H20AuN3O2P(1+)*CF3O3S(1-); water; silver trifluoromethanesulfonate; acetic acid at 100℃; for 10h; | 91% |
With water at 200℃; for 0.333333h; microwave irradiation; | 90% |
bis-(3-acetyl-phenyl)-diazene
1-(3-aminophenyl)ethanone
Conditions | Yield |
---|---|
With zinc; hydrazinium monoformate In methanol for 0.1h; Heating; | 93% |
With ammonium formate; magnesium In methanol at 20℃; for 0.15h; | 91% |
With ammonium chloride; zinc In methanol at 20℃; for 0.2h; | 91% |
Conditions | Yield |
---|---|
With ethanol; titanium(IV) oxide for 0.25h; Irradiation; | A 92% B n/a C n/a |
tributylgermanium hydride
3-(azidophenyl) methyl ketone
C
1-(3-aminophenyl)ethanone
Conditions | Yield |
---|---|
With thiophenol In toluene for 0.5h; Heating; | A 1% B 2% C 92% |
Conditions | Yield |
---|---|
With copper(I) oxide; ammonium hydroxide In 1-methyl-pyrrolidin-2-one at 80℃; for 15h; | 92% |
With copper(I) oxide; ammonium hydroxide; N1-(furan-2-ylmethyl)-N2-(2-methylnaphthalen-1-yl)oxalamide; potassium hydroxide In ethanol at 80℃; for 24h; Schlenk technique; Inert atmosphere; | 64% |
Stage #1: 1-(3-Bromophenyl)ethanone With copper(l) iodide; D-glucosamine hydrochloride; potassium carbonate In water; acetone at 90℃; for 0.166667h; Stage #2: With ammonia In water; acetone at 90℃; for 30h; | 62% |
1-(3-aminophenyl)ethanone
Conditions | Yield |
---|---|
With indium; ammonium chloride In ethanol for 2.5h; Heating; | 91% |
(E)-1,1'-(diazene-1,2-diyl)bis(1,3-phenylene)bis(ethan-1-one)
1-(3-aminophenyl)ethanone
Conditions | Yield |
---|---|
With nickel; hydrazinium monoformate In methanol for 0.15h; Heating; | 90% |
3-(azidophenyl) methyl ketone
1-(3-aminophenyl)ethanone
Conditions | Yield |
---|---|
With samarium diiodide In tetrahydrofuran for 1.25h; Ambient temperature; | 89% |
With tellurium; water at 275℃; for 4h; | 89% |
With ammonium formate; copper In water for 8h; Reflux; chemoselective reaction; | 84% |
1-(3-aminophenyl)ethanone
Conditions | Yield |
---|---|
With N-Bromosuccinimide; CYANAMID; bis-[(trifluoroacetoxy)iodo]benzene In acetonitrile at 20℃; for 1h; Reagent/catalyst; chemoselective reaction; | 87% |
With N-Bromosuccinimide; N-methoxylamine hydrochloride; bis-[(trifluoroacetoxy)iodo]benzene In acetonitrile at 20℃; | 78% |
Toxicological Data on Ingredients: 3-Aminoacetophenone: ORAL (LD50): Acute: 1870 mg/kg [Rat.]. DERMAL (LD50):
Acute: 4340 mg/kg [Rabbit.].
Hazardous in case of eye contact (irritant), of inhalation. Slightly hazardous in case of skin contact (irritant,permeator), of ingestion.
Toxicity of 3-amino acetophenone of Biodegradation: 3-amino acetophenone of degradation are more toxic.