Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

3-Bromo-4-fluorobenzotrifluoride
Related Products

Hot Products

Basic Information Post buying leads Suppliers Cas Database
Name

3-Bromo-4-fluorobenzotrifluoride

 EINECS N/A
CAS No. 68322-84-9 Density 1.706 g/cm3
PSA 0.00000 LogP 3.60700
Solubility N/A Melting Point N/A
Formula C7H3BrF4 Boiling Point 152.7 °C at 760 mmHg
Molecular Weight 242.998 Flash Point 59 °C
Transport Information UN 1760 Appearance clear colorless liquid
Safety 45-36/37/39-26 Risk Codes 34-36/37/38-20/21/22
Molecular Structure Molecular Structure of 68322-84-9 (3-Bromo-4-fluorobenzotrifluoride) Hazard Symbols HarmfulXn,CorrosiveC,IrritantXi
Synonyms

2-Bromo-1-fluoro-4-trifluoromethylbenzene;2-Bromo-4-trifluoromethyl-1-fluorobenzene;2-Fluoro-5-(trifluoromethyl)bromobenzene;2-Fluoro-5-trifluoromethyl-1-bromobenzene;

Article Data 2

3-Bromo-4-fluorobenzotrifluoride Synthetic route

402-44-8

4-Fluorobenzotrifluoride

68322-84-9

2-bromo-1-fluoro-4-(trifluoromethyl)benzene

Conditions
ConditionsYield
With ferric(III) bromide; sulfuric acid; tetrabutylammomium bromide; bromine; lithium bromide at 35 - 45℃; for 6h;95.94%
68322-84-9

2-bromo-1-fluoro-4-(trifluoromethyl)benzene

73183-34-3

bis(pinacol)diborane

2-[3-bromo-2-fluoro-5-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3 ,2-dioxaborolane

Conditions
ConditionsYield
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; cyclopentyl methyl ether; 1,1'-di(pyridin-2-yl)-1,1',3,3'-tetrahydro-2,2'-bibenzo[d][1,3,2]diazaborole at 100℃; for 16h; Schlenk technique; Inert atmosphere;100%
With bis(1,5-cyclooctadiene)diiridium(I) dichloride; 1-(4,4'-di-tert-butyl-[2,2'-bipyridin]-6-yl)-2-(dimethyl(phenyl)silyl)-2,3-dihydro-1H-benzo[d][1,3,2]diazaborole Inert atmosphere; Schlenk technique; Sealed tube;98%
With (1,5-cyclooctadiene)(methoxy)iridium(l) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine In tetrahydrofuran at 80℃; for 24h; Inert atmosphere;
68322-84-9

2-bromo-1-fluoro-4-(trifluoromethyl)benzene

55499-44-0

2,4-dimethylbenzeneboronic acid

2'-fluoro-2,4-dimethyl-5'-(trifluoromethyl)-1,1'-biphenyl

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,2-dimethoxyethane; water at 80℃; for 8h; Suzuki-Miyaura Coupling; Inert atmosphere;99%
68322-84-9

2-bromo-1-fluoro-4-(trifluoromethyl)benzene

123324-71-0

4-tert-butylphenylboronic acid

4'-(tert-butyl)-2-fluoro-5-(trifluoromethyl)-1,1'-biphenyl

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,2-dimethoxyethane; water at 80℃; for 12h; Suzuki-Miyaura Coupling; Inert atmosphere;98%
533-58-4

2-Iodophenol

68322-84-9

2-bromo-1-fluoro-4-(trifluoromethyl)benzene

1325219-84-8

2-bromo-1-(2-iodophenoxy)-4-(trifluoromethyl)benzene

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 95℃; for 20h; Inert atmosphere;95%
With potassium carbonate In dimethyl sulfoxide at 95℃; for 48h; Sealed tube;91%
621-59-0

isovanillin

68322-84-9

2-bromo-1-fluoro-4-(trifluoromethyl)benzene

1188267-41-5

3-(2-bromo-4-trifluoromethyl-phenoxy)-4-methoxy-benzaldehyde

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20 - 140℃; for 5.25h; Inert atmosphere;94%
850793-73-6

3-[4-(3-hydroxy-4-methyl-phenoxy)-2-methyl-phenyl]propionic acid ethyl ester

68322-84-9

2-bromo-1-fluoro-4-(trifluoromethyl)benzene

3-{4-[3-(2-bromo-4-trifluoromethyl-phenoxy)-4-methyl-phenoxy]-2-methyl-phenyl}propionic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 100℃; for 6h; Heating;88%
68322-84-9

2-bromo-1-fluoro-4-(trifluoromethyl)benzene

123088-32-4

4-tert-butyl-dimethylsilyloxyphenylboronic acid anhydride

2'-fluoro-5'-trifluoromethyl-biphenyl-4-ol

Conditions
ConditionsYield
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,2-dimethoxyethane; water at 95℃; Suzuki reaction;87%
68322-84-9

2-bromo-1-fluoro-4-(trifluoromethyl)benzene

81107-97-3

2-bromo-4-(trifluoromethyl)phenol

Conditions
ConditionsYield
With acetylhydroxamic acid; potassium carbonate In dimethyl sulfoxide at 80℃; for 18h; Sealed tube;86%
850793-70-3

3-[4-(5-hydroxy-2-methyl-phenoxy)-2-methyl-phenyl]propionic acid ethyl ester

68322-84-9

2-bromo-1-fluoro-4-(trifluoromethyl)benzene

3-{4-[5-(2-bromo-4-trifluoromethyl-phenoxy)-2-methyl-phenoxy]-2-methyl-phenyl}propionic acid ethyl ester

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 100℃; for 6h; Heating;81%

3-Bromo-4-fluorobenzotrifluoride Specification

The 4-Fluoro-3-bromobenzotrifluoride, with the CAS registry number 68322-84-9, is also known as 2-Fluoro-5-(trifluoromethyl)bromobenzene. It belongs to the product categories of Trifluoromethylbenzene Serise; Fluorobenzene; Miscellaneous; Benzotrifluoride Series; Aryl; C7; Halogenated Hydrocarbons. This chemical's molecular formula is C7H3BrF4 and molecular weight is 242.996333. Its IUPAC name is called 2-bromo-1-fluoro-4-(trifluoromethyl)benzene. The product should be sealed and stored in cool and dry place. What's more, it should be protected from strong oxides. It is a intermediate used in the fields of medicine and pesticide.

Physical properties of 4-Fluoro-3-bromobenzotrifluoride: (1)ACD/LogP: 3.33; (2)ACD/LogD (pH 5.5): 3.33; (3)ACD/LogD (pH 7.4): 3.33; (4)ACD/BCF (pH 5.5): 200.64; (5)ACD/BCF (pH 7.4): 200.64; (6)ACD/KOC (pH 5.5): 1547.68; (7)ACD/KOC (pH 7.4): 1547.68; (8)Index of Refraction: 1.455; (9)Molar Refractivity: 38.91 cm3; (10)Molar Volume: 143.3 cm3; (11)Surface Tension: 25.4 dyne/cm; (12)Density: 1.695 g/cm3; (13)Flash Point: 59 °C; (14)Enthalpy of Vaporization: 37.35 kJ/mol; (15)Boiling Point: 152.7 °C at 760 mmHg; (16)Vapour Pressure: 4.42 mmHg at 25°C.

Uses of 4-Fluoro-3-bromobenzotrifluoride: it can be used to produce [2-(2-bromo-4-trifluoromethyl-phenoxy)-ethyl]-trimethyl-silane at temperature of 20 °C. This reaction will need reagent KHMDS and solvents tetrahydrofuran, toluene with reaction time of 1 hour. The yield is about 59%.

4-Fluoro-3-bromobenzotrifluoride can be used to produce [2-(2-bromo-4-trifluoromethyl-phenoxy)-ethyl]-trimethyl-silane

When you are using this chemical, please be cautious about it as the following:
This chemical may cause inflammation to the skin or other mucous membranes. It is harmful by inhalation, in contact with skin and if swallowed. Meanwhile, it is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1=CC(=C(C=C1C(F)(F)F)Br)F
(2)InChI: InChI=1S/C7H3BrF4/c8-5-3-4(7(10,11)12)1-2-6(5)9/h1-3H
(3)InChIKey: RZJOIMPUMMQKFR-UHFFFAOYSA-N

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 68322-84-9