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3-Phenylpiperidine

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Name

3-Phenylpiperidine

EINECS 223-602-7
CAS No. 3973-62-4 Density 0.967 g/cm3
PSA 12.03000 LogP 2.48240
Solubility N/A Melting Point 142-143℃
Formula C11H15N Boiling Point 263.183 °C at 760 mmHg
Molecular Weight 161.247 Flash Point 115.488 °C
Transport Information N/A Appearance N/A
Safety 26-36/37/39 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 3973-62-4 (3-PHENYLPIPERIDINE) Hazard Symbols IrritantXi
Synonyms

3-Phenylpiperidine;

Article Data 29

3-Phenylpiperidine Synthetic route

1008-88-4

3-phenylpyridine

3973-62-4

3-phenylpiperidine

Conditions
ConditionsYield
With hydrogen In water at 140℃; under 45004.5 Torr; for 24h; Autoclave; chemoselective reaction;98%
With triphenylborane; diphenylsilane; diphenylamine In toluene at 110℃; for 24h; Glovebox; Inert atmosphere; chemoselective reaction;90%
With palladium diacetate; C3H6BNO2 In tetrahydrofuran at 60℃; for 24h; Schlenk technique; Inert atmosphere;87.3%
3979-67-7

N-benzyl-3-phenylpiperidine

3973-62-4

3-phenylpiperidine

Conditions
ConditionsYield
With 18 % Pd/C; hydrogen; acetic acid In ethanol at 60℃; under 760.051 Torr; for 12h;89.3%

N-benzyl-5-phenyl-1,2,3,6-tetrahydropyridine

A

3973-62-4

3-phenylpiperidine

B

3979-67-7

N-benzyl-3-phenylpiperidine

Conditions
ConditionsYield
With palladium on activated charcoal Hydrogenation;
3973-63-5

5-phenylpiperidin-2-one

3973-62-4

3-phenylpiperidine

Conditions
ConditionsYield
With sodium tetrahydroborate; boron trifluoride diethyl etherate In tetrahydrofuran 1) r.t., 2 h, 2) reflux, 2 h; Yield given;
(+-)-1-benzyl-3-phenyl-piperidine

(+-)-1-benzyl-3-phenyl-piperidine

3973-62-4

3-phenylpiperidine

Conditions
ConditionsYield
With palladium on activated charcoal; ethanol Hydrogenation;
(+-)-2-phenyl-glutaronitrile

(+-)-2-phenyl-glutaronitrile

3973-62-4

3-phenylpiperidine

Conditions
ConditionsYield
With sodium; butan-1-ol
(+-)-3-acetoxy-1-benzyl-3-phenyl-piperidine

(+-)-3-acetoxy-1-benzyl-3-phenyl-piperidine

3973-62-4

3-phenylpiperidine

Conditions
ConditionsYield
With palladium on activated charcoal; ethanol Hydrogenation;
(+-)-3-phenyl-piperidine-2,6-dione

(+-)-3-phenyl-piperidine-2,6-dione

3973-62-4

3-phenylpiperidine

Conditions
ConditionsYield
With lithium aluminium tetrahydride; diethyl ether
(+-)-5-phenoxy-2-phenyl-pentylamine

(+-)-5-phenoxy-2-phenyl-pentylamine

3973-62-4

3-phenylpiperidine

Conditions
ConditionsYield
With hydrogen bromide anschliessend Erhitzen in Toluol mit wss. Natronlauge;
(+-)-5-phenyl-piperidin-2-one

(+-)-5-phenyl-piperidin-2-one

3973-62-4

3-phenylpiperidine

Conditions
ConditionsYield
With sodium; butan-1-ol

3-Phenylpiperidine Specification

The CAS register number of Piperidine, 3-phenyl- is 3973-62-4. It also can be called as (S)-3-Phenyl piperidine and the IUPAC name about this chemical is 3-phenylpiperidine. The molecular formula about this chemical is C11H15N and the molecular weight is 161.24. It belongs to the Piperidine.

Physical properties about Piperidine, 3-phenyl- are: (1)ACD/LogP: 2.38; (2)ACD/BCF (pH 5.5): 1; (3)ACD/BCF (pH 7.4): 1; (4)ACD/KOC (pH 5.5): 1; (5)ACD/KOC (pH 7.4): 1.508; (6)#H bond acceptors: 1; (7)#H bond donors: 1; (8)#Freely Rotating Bonds: 1; (9)Polar Surface Area: 12.03Å2; (10)Index of Refraction: 1.522; (11)Molar Refractivity: 50.851 cm3; (12)Molar Volume: 166.671 cm3; (13)Polarizability: 20.159x10-24cm3; (14)Surface Tension: 35.352 dyne/cm; (15)Enthalpy of Vaporization: 50.1 kJ/mol; (16)Boiling Point: 263.183 °C at 760 mmHg; (17)Vapour Pressure: 0.01 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable protective clothing, gloves and eye/face protection. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: c1ccc(cc1)C2CCCNC2
(2)InChI: InChI=1/C11H15N/c1-2-5-10(6-3-1)11-7-4-8-12-9-11/h1-3,5-6,11-12H,4,7-9H2
(3)InChIKey: NZYBILDYPCVNMU-UHFFFAOYAD
(4)Std. InChI: InChI=1S/C11H15N/c1-2-5-10(6-3-1)11-7-4-8-12-9-11/h1-3,5-6,11-12H,4,7-9H2
(5)Std. InChIKey: NZYBILDYPCVNMU-UHFFFAOYSA-N

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