- 1204-28-05-Isobenzofurancarbonylchloride, 1,3-dihydro-1,3-dioxo-
- 12042-91-0Aluminum chlorhydroxide
- 1204-32-61H-Indole-6-carboxylicacid, 1-methyl-, methyl ester
- 12043-29-7Aluminum telluride(Al2Te3)
- 1204333-58-3Pyridine, 2,6-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
- 120-43-41-Piperazinecarboxylicacid, ethyl ester
- 1204355-48-51-tert-butyl-5-phenyl-1H-pyrazole
- 1204-35-91H-Pyrrole-2,5-dione,1-(3-chlorophenyl)-
- 12043-90-2Undecaaluminium lanthanum octadecaoxide
- 1204400-58-76-chloro-3-nitropyridine-2-carboxylic acid
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
4-(2-Bromoethyl)-2-oxoindole |
EINECS | 1308068-626-2 |
| CAS No. | 120427-96-5 | Density | 1.529 g/cm3 |
| PSA | 29.10000 | LogP | 2.25660 |
| Solubility | N/A | Melting Point |
153-155°C |
| Formula | C10H10BrNO | Boiling Point | 373.798 °C at 760 mmHg |
| Molecular Weight | 240.099 | Flash Point | 179.867 °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
4-(2-Bromoethyl)-1,3-dihydro-2H-indol-2-one;4-(2-Bromoethyl)indolin-2-one; |
Article Data | 7 |
4-(2-Bromoethyl)-2-oxoindole Synthetic route
- 120427-95-4
4-(2-bromoethyl)-3-chloro-1,3-dihydro-2H-indolin-2-one
- 120427-96-5
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
| Conditions | Yield |
|---|---|
| With sodium hypophosphite; palladium on activated charcoal In ethyl acetate for 0.583333h; Heating; | 95% |
| With sodium hypophosphite monohydrate; palladium on activated charcoal In water; ethyl acetate Large scale; | 95% |
| With sodium hypophosphite hydrate; palladium 10% on activated carbon In water; ethyl acetate for 1h; Heating / reflux; | 88.97% |
| With phosphonic Acid; sodium iodide In ethanol at 70℃; for 5h; Reagent/catalyst; | 86.7% |
- 22901-09-3
2-(2-bromoethyl)benzaldehyde
- 120427-96-5
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: 80 percent / MeONa / methanol / 1 h / 0 °C 2: 53 percent / AcCl, FeCl3 / CH2Cl2 / 3 h / 0 - 5 °C 3: 95 percent / aq. NaH2PO2 / 10percent Pd-C / ethyl acetate / 0.58 h / Heating View Scheme |
- 120427-96-5
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: 53 percent / AcCl, FeCl3 / CH2Cl2 / 3 h / 0 - 5 °C 2: 95 percent / aq. NaH2PO2 / 10percent Pd-C / ethyl acetate / 0.58 h / Heating View Scheme |
- 7440-44-0
pyrographite
- 7440-05-3
palladium
- 120427-95-4
4-(2-bromoethyl)-3-chloro-1,3-dihydro-2H-indolin-2-one
- 120427-96-5
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
| Conditions | Yield |
|---|---|
| In water |
- 120427-95-4
4-(2-bromoethyl)-3-chloro-1,3-dihydro-2H-indolin-2-one
- 120427-96-5
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
| Conditions | Yield |
|---|---|
| carbon palladium In water | 17.0 g (82%) |
- 493-05-0
isochromane
- 120427-96-5
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1: bromine / water / Irradiation 2: water; methanol / Acidic conditions; Large scale 3: iron(III) chloride / Acidic conditions; Large scale 4: palladium on activated charcoal; sodium hypophosphite monohydrate / water; ethyl acetate / Large scale View Scheme | |
| Multi-step reaction with 7 steps 1: zinc(II) chloride / dichloromethane / Reflux 2: hexamethylenetetramine; acetic acid / ethanol; water 3: N-butylamine; acetic acid; nitromethane / methanol / 20 °C 4: iron(III) chloride / dichloromethane / 0 - 5 °C 5: hydrazine hydrate; palladium 10% on activated carbon / methanol 6: sodium hydroxide; water / methanol / Reflux 7: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C View Scheme |
- 50683-32-4
1-Bromoisochromane
- 120427-96-5
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: water; methanol / Acidic conditions; Large scale 2: iron(III) chloride / Acidic conditions; Large scale 3: palladium on activated charcoal; sodium hypophosphite monohydrate / water; ethyl acetate / Large scale View Scheme |
- 120427-96-5
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: iron(III) chloride / Acidic conditions; Large scale 2: palladium on activated charcoal; sodium hypophosphite monohydrate / water; ethyl acetate / Large scale View Scheme |
- 139122-17-1
4-[2-(benzoyloxy)ethyl]-3-chloro-1,3-dihydro-2H-indolin-2-one
- 120427-96-5
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: hydrazine hydrate; palladium 10% on activated carbon / methanol 2: sodium hydroxide; water / methanol / Reflux 3: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C View Scheme |
- 139122-18-2
4-(2-benzoyloxyethyl)-1,3-dihydro-2H-indolin-2-one
- 120427-96-5
4-(2'-bromoethyl)-1,3-dihydro-2H-indol-2-one
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: sodium hydroxide; water / methanol / Reflux 2: carbon tetrabromide; triphenylphosphine / dichloromethane / 0 - 20 °C View Scheme |
4-(2-Bromoethyl)-2-oxoindole Specification
The 4-(2-Bromoethyl)-2-oxoindole, with the CAS registry number 120427-96-5, is also known as 4-(2-Bromoethyl)-1,3-dihydro-2H-indol-2-one. It belongs to the product category of Pharmaceutical Material and Intermeidates. This chemical's molecular formula is C10H10BrNO and molecular weight is 240.10. What's more, its systematic name is called 2H-Indol-2-one, 4-(2-bromoethyl)-. It is a useful synthetic intermediate.
Physical properties about 4-(2-Bromoethyl)-2-oxoindole are: (1) ACD/LogP: 1.35; (2) # of Rule of 5 Violations: 0; (3) ACD/LogD (pH 5.5): 1.35; (4) ACD/LogD (pH 7.4): 1.35; (5) ACD/BCF (pH 5.5): 6.24; (6) ACD/BCF (pH 7.4): 6.24; (7) ACD/KOC (pH 5.5): 128.99; (8) ACD/KOC (pH 7.4): 128.99; (9) #H bond acceptors: 2; (10) #H bond donors: 0; (11) #Freely Rotating Bonds: 2; (12) Polar Surface Area: 29.43 Å2; (13) Index of Refraction: 1.648; (14) Molar Refractivity: 54.99 cm3; (15) Molar Volume: 151 cm3; (16) Surface Tension: 49.1 dyne/cm; (17) Density: 1.57 g/cm3; (18) Flash Point: 182.4 °C; (19) Enthalpy of Vaporization: 62.58 kJ/mol; (20) Boiling Point: 378 °C at 760 mmHg; (21) Vapour Pressure: 6.49E-06 mmHg at 25 °C.
You can still convert the following datas into molecular structure:
(1) SMILES:c1cc(c2=CC(=O)N=c2c1)CCBr
(2) InChI: InChI=1/C10H8BrNO/c11-5-4-7-2-1-3-9-8(7)6-10(13)12-9/h1-3,6H,4-5H2
(3) InChIKey: KEFXEJHKEJPEOB-UHFFFAOYAI
What can I do for you?
Get Best Price
