Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

4-Hydroxy-3-nitrobenzoic acid

Related Products

Hot Products

Name

4-Hydroxy-3-nitrobenzoic acid

EINECS 210-494-1
CAS No. 616-82-0 Density 1.632 g/cm3
PSA 103.35000 LogP 1.52180
Solubility N/A Melting Point 183-186 °C(lit.)
Formula C7H5NO5 Boiling Point 354.304 °C at 760 mmHg
Molecular Weight 183.12 Flash Point 162.528 °C
Transport Information N/A Appearance yellow to light brown powder
Safety 26-37/39-24/25-36 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 616-82-0 (4-Hydroxy-3-nitrobenzoic acid) Hazard Symbols HarmfulXn,IrritantXi
Synonyms

3-Nitro-4-hydroxybenzoicacid;4-Carboxy-2-nitrophenol;NSC 78436;p-Hydroxy-m-nitrobenzoic acid;3-Nitro-4-hydroxybenzoic acid;

Article Data 66

4-Hydroxy-3-nitrobenzoic acid Synthetic route

99-96-7

4-hydroxy-benzoic acid

616-82-0

3-nitro-4-hydroxybenzoic acid

Conditions
ConditionsYield
With magnesium(II) nitrate hexahydrate; AMA at 20℃; for 1.5h; Neat (no solvent); regioselective reaction;98%
With dimethylbromosulphonium bromide; tetrabutylammonium nitrite In acetonitrile at 20℃; for 2h; regioselective reaction;93%
With trichloroisocyanuric acid; silica gel; sodium nitrite In dichloromethane at 20℃; for 0.333333h;87%
96-99-1

4-chloro-3-nitrobenzoate

616-82-0

3-nitro-4-hydroxybenzoic acid

Conditions
ConditionsYield
With water; sodium hydroxide at 100℃;98%
With sodium hydroxide In water at 95℃; for 10h;91.83%
With sodium hydroxide In water430 g (90 %)
453-71-4

3-nitro-4-fluorobenzoic acid

616-82-0

3-nitro-4-hydroxybenzoic acid

Conditions
ConditionsYield
With acetylhydroxamic acid; potassium carbonate In dimethyl sulfoxide at 80℃; for 1h; Sealed tube;93%
99-96-7

4-hydroxy-benzoic acid

A

100-02-7

4-nitro-phenol

B

616-82-0

3-nitro-4-hydroxybenzoic acid

Conditions
ConditionsYield
With ammonium cerium(IV) nitrate In acetonitrile at 20℃; for 0.333333h;A 10%
B 84%
99-96-7

4-hydroxy-benzoic acid

A

51-28-5

2,4-Dinitrophenol

B

616-82-0

3-nitro-4-hydroxybenzoic acid

Conditions
ConditionsYield
With ammonium cerium(IV) nitrate In acetonitrile at 60 - 70℃; for 0.25h;A 45%
B 50%
With ammonium cerium(IV) nitrate In acetonitrile at 60 - 70℃; for 0.25h;A 50%
B 50%
With chloroform; nitric acid
619-57-8

p-hydroxybenzamide

A

616-82-0

3-nitro-4-hydroxybenzoic acid

B

74230-08-3

2-nitro-4-hydroxybenzoic acid

C

99-96-7

4-hydroxy-benzoic acid

Conditions
ConditionsYield
With acetic acid; isopentyl nitrite at 80℃; for 21h; Inert atmosphere;A 39%
B 43%
C 13%
99-50-3

3,4-Dihydroxybenzoic acid

A

51-28-5

2,4-Dinitrophenol

B

616-82-0

3-nitro-4-hydroxybenzoic acid

Conditions
ConditionsYield
With diethyl ether; cis-nitrous acid
623-11-0

1-methyl-4-nitrosobenzene

528-45-0

3,4-dinitrobenzoic acid

616-82-0

3-nitro-4-hydroxybenzoic acid

623-11-0

1-methyl-4-nitrosobenzene

(4-methoxycarbonyl-2-nitro-phenoxy)-acetic acid

616-82-0

3-nitro-4-hydroxybenzoic acid

623-11-0

1-methyl-4-nitrosobenzene

476313-40-3

4-methoxycarbonylmethoxy-3-nitro-benzoic acid

616-82-0

3-nitro-4-hydroxybenzoic acid

4-Hydroxy-3-nitrobenzoic acid Specification

The 4-Hydroxy-3-nitrobenzoic acid, with the CAS registry number 616-82-0, is also known as 3-Nitro-4-hydroxybenzoic acid. It belongs to the product categories of Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts; Organic acids; C7; Carbonyl Compounds;Carboxylic Acids. Its EINECS number is 210-494-1. This chemical's molecular formula is C7H5NO5 and molecular weight is 183.12. What's more, its systematic name is Ethyl hydrazinecarboxylate. Its storage temperature is 0°C. This chemical is used as a pharmaceutical intermediate.

Physical properties of 4-Hydroxy-3-nitrobenzoic acid are: (1)ACD/LogP: 1.904; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.08; (4)ACD/LogD (pH 7.4): -1.89; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 3.91; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 6; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 103.35 Å2; (13)Index of Refraction: 1.664; (14)Molar Refractivity: 41.61 cm3; (15)Molar Volume: 112.234 cm3; (16)Polarizability: 16.495×10-24cm3; (17)Surface Tension: 84.1 dyne/cm; (18)Density: 1.632 g/cm3; (19)Flash Point: 162.528 °C; (20)Enthalpy of Vaporization: 63.243 kJ/mol; (21)Boiling Point: 354.304 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. When using it, you must avoid contact with skin and eyes. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)SMILES: O=[N+]([O-])c1cc(ccc1O)C(=O)O
(2)Std. InChI: InChI=1S/C7H5NO5/c9-6-2-1-4(7(10)11)3-5(6)8(12)13/h1-3,9H,(H,10,11)
(3)Std. InChIKey: QRYSWXFQLFLJTC-UHFFFAOYSA-N 

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 616-82-0