Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

5alpha-Androst-16-en-3beta-ol
Related Products

Hot Products

Basic Information Post buying leads Suppliers Cas Database
Name

5alpha-Androst-16-en-3beta-ol

 EINECS 214-573-1
CAS No. 7148-51-8 Density 1.037 g/cm3
PSA 20.23000 LogP 4.55610
Solubility N/A Melting Point 123-124 °C
Formula C19H30O Boiling Point 374.1 °C at 760 mmHg
Molecular Weight 274.447 Flash Point 156.5 °C
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 7148-51-8 (16,(5-ALPHA)-ANDROSTEN-3-BETA-OL) Hazard Symbols N/A
Synonyms

5a-Androst-16-en-3b-ol (6CI,7CI,8CI);3b-Hydroxy-5a-androst-16-ene;JNF 55;NSC65888;

Article Data 27

5alpha-Androst-16-en-3beta-ol Synthetic route

18339-16-7

5α-androst-16-en-3-one

A

7148-51-8

5α-androst-16-en-3β-ol

B

3597-54-4, 4572-71-8, 7148-51-8, 14152-27-3, 18485-74-0, 19321-55-2, 64681-01-2, 86335-09-3, 86335-14-0, 86335-15-1, 103615-88-9, 103615-90-3, 1153-51-1

androstenol

Conditions
ConditionsYield
With sodium tetrahydroborate In tetrahydrofuran; methanol for 2h; Ambient temperature;A 77%
B 2%
With aluminum isopropoxide; isopropyl alcohol Isolierung ueber die in wss. Aethanol schwer loesliche Verbindung mit Digitonin;
With ethanol; water; lithium tri-sec-butyl(hydrido)borate 1.) THF, r.t., 3 h; 2.) -55 deg C; Yield given. Multistep reaction. Yields of byproduct given;
95043-81-5

17-iodo-3β-hydroxy-5α-androstan-16-ene

7148-51-8

5α-androst-16-en-3β-ol

Conditions
ConditionsYield
With diethylene glycol monoethyl ether sodium salt In 1,4-dioxane at 100℃; for 92h; Reagent/catalyst; Temperature; Solvent; Inert atmosphere;75.4%
With ethanol; sodium Heating;
With sodium In ethanol Reflux;
939496-37-4

16R-bromopregnane-3S,20S-diol

A

16S,20S-epoxypregnane-3S-ol

B

7148-51-8

5α-androst-16-en-3β-ol

Conditions
ConditionsYield
With potassium tert-butylate In tert-butyl alcohol at 60℃; for 18h;A 65%
B 30%
With potassium tert-butylate In tert-butyl alcohol at 82℃; for 5h;A 46%
B 52%
481-29-8

Epiandrosterone

7148-51-8

5α-androst-16-en-3β-ol

Conditions
ConditionsYield
Stage #1: Epiandrosterone With toluene-4-sulfonic acid hydrazide In ethanol for 2h; Bamford-Stevens Decomposition; Reflux;
Stage #2: With methyllithium In diethyl ether at 22℃; for 16.5h; Bamford-Stevens Decomposition;		29%
18339-16-7

5α-androst-16-en-3-one

7148-51-8

5α-androst-16-en-3β-ol

Conditions
ConditionsYield
With lithium aluminium tetrahydride; diethyl ether
18339-16-7

5α-androst-16-en-3-one

555-31-7

aluminum isopropoxide

67-63-0

isopropyl alcohol

A

7148-51-8

5α-androst-16-en-3β-ol

B

3597-54-4, 4572-71-8, 7148-51-8, 14152-27-3, 18485-74-0, 19321-55-2, 64681-01-2, 86335-09-3, 86335-14-0, 86335-15-1, 103615-88-9, 103615-90-3, 1153-51-1

androstenol

72203-76-0

5α-androst-16-en-3β-yl acetate

7148-51-8

5α-androst-16-en-3β-ol

Conditions
ConditionsYield
With potassium hydroxide In methanol
94438-53-6

17-bromo-3β-hydroxy-5α-androstan-16-ene

7148-51-8

5α-androst-16-en-3β-ol

Conditions
ConditionsYield
With ethanol; sodium Heating;
17320-46-6

17-chloro-3β-hydroxy-5α-androstan-16-ene

7148-51-8

5α-androst-16-en-3β-ol

Conditions
ConditionsYield
With sodium amide In diethyl ether
With ethanol; sodium
With ethanol; sodium Heating;
521-18-6

Stanolone

7148-51-8

5α-androst-16-en-3β-ol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 92 percent / pyridine / 24 h / 0 °C
2: 87 percent / toluene / 480 °C
3: 1.) lithium tris(1,2-dimethylpropyl)hydridoborate; 2.) water, ethanol / 1.) THF, r.t., 3 h; 2.) -55 deg C
View Scheme

5alpha-Androst-16-en-3beta-ol Specification

The IUPAC name of 5alpha-Androst-16-en-3beta-ol is (3S,5S,8R,9S,10S,13R,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol. With the CAS registry number 7148-51-8, it is also named as 16,(5-alpha)-Androsten-3-beta-ol. The product's categories are Intermediates & Fine Chemicals; Metabolites & Impurities; Pharmaceuticals; Steroids. It is a metabolite of 16-Androstene.

The other characteristics of 5alpha-Androst-16-en-3beta-ol can be summarized as: (1)ACD/LogP: 5.88; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 5.88; (4)ACD/LogD (pH 7.4): 5.88; (5)ACD/BCF (pH 5.5): 17447; (6)ACD/BCF (pH 7.4): 17447; (7)ACD/KOC (pH 5.5): 37827.77; (8)ACD/KOC (pH 7.4): 37827.77; (9)#H bond acceptors: 1; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 1; (12)Index of Refraction: 1.54; (13)Molar Refractivity: 82.96 cm3; (14)Molar Volume: 264.4 cm3; (15)Polarizability: 32.89×10-24 cm3; (16)Surface Tension: 41.1 dyne/cm; (17)Enthalpy of Vaporization: 71.9 kJ/mol; (18)Vapour Pressure: 4E-07 mmHg at 25°C; (19)Exact Mass: 274.229666; (20)MonoIsotopic Mass: 274.229666; (21)Topological Polar Surface Area: 20.2; (22)Heavy Atom Count: 20; (23)Complexity: 428; (24)Defined Atom StereoCenter Count: 7.

People can use the following data to convert to the molecule structure. 
1. SMILES:O[C@@H]4C[C@@H]3CC[C@H]2[C@H]1[C@@](/C=C\C1)(CC[C@@H]2[C@@]3(C)CC4)C
2. InChI:InChI=1/C19H30O/c1-18-9-3-4-16(18)15-6-5-13-12-14(20)7-11-19(13,2)17(15)8-10-18/h3,9,13-17,20H,4-8,10-12H2,1-2H3/t13-,14-,15-,16-,17-,18-,19-/m0/s1
3. InChIKey:KRVXMNNRSSQZJP-LOVVWNRFBX

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 7148-51-8