Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
6-Hydroxy-2-naphthaleneboronic acid |
EINECS | N/A |
CAS No. | 173194-95-1 | Density | 1.358 g/cm3 |
PSA | 60.69000 | LogP | 0.22520 |
Solubility | N/A | Melting Point |
218-224 °C |
Formula | C10H9BO3 | Boiling Point | 458.567 °C at 760 mmHg |
Molecular Weight | 187.991 | Flash Point | 231.134 °C |
Transport Information | N/A | Appearance | N/A |
Safety | 26-36/37/39 | Risk Codes | 36/37/38 |
Molecular Structure | Hazard Symbols | Xi | |
Synonyms |
(6-Hydroxynaphthalen-2-yl)boronic acid;Boronic acid,(6-hydroxy-2-naphthalenyl)- (9CI); |
Article Data | 3 |
A review of luminescent assays has been published by L. J. Kricka, Clinical Chemistry 37, 1472-1481 (1991).
SUMMARY OF THE INVENTION
It has now been found that certain organoboron compounds are effective enhancers of chemiluminescence in a reaction between a dihydrophthalaztnedione (DPD), a peroxidase enzyme catalyst and an oxidant. The enhancers of the present Invention include compounds of formula which R, W, X, Y and Z have the following meanings; R is selected from hydrogen, n-butyl, O,O-propylene (a cyclic ether), 4'-chlorophenyl and 3',5'-dichlorophenyl, W is selected from hydrogen, hydroxy, methyl, methoxy and chloro, X Is selected from hydrogen, methyl, chloro, amino and nitro, Y is selected from hydrogen, methyl, carboxy, chloro, bromo, iodo, phenyl, phenoxy, 4'-chloroanilino, 4'-boronylphenyl, 4'-bromophenyl, 2'-carboxyethenyl and trimethylsilyl, Z is selected from hydrogen, 5-chloro, 5-bromo, 5-(3'-trifluoromethyl)phenylazo, or 6-chloro, W and X together may represent a fused benzene ring and X and Y together may represent a fused benzene ring substituted by hydroxy in the 6 position of the naphthalene ring numbering, provided that