- 7-α-ETORPHINE
- 7-β,8-α-9-β,10-β-TETRAHYDROXY-7,8,9,10-TETRAHYDROBENZO(a)PYRENE
- 7-(((2-Pyrrolyl)methyl)amino)-actinomycin D
- 7-((2-((2-Chloroethyl)amino)ethyl)amino)benz(c)acridine dihydrochloride hydrate
- 7-((3-((2-Chloroethyl)amino)propyl)amino)benz(c)acridine dihydrochloride sesquihydrate
- 7-((3-((2-Chloroethyl)amino)propyl)amino)benzo(b)(1,8)phenanthroline dihydrochloride hydrate
- 7-((3-((2-Chloroethyl)ethylamino)propyl)amino)benzo(b)(1,10)phenanthroline dihydrochloride
- 7-((3,4-Dichlorobenzyl)amino)-actinomycin D
- 7-((p-(Dimethylamino)phenyl)azo)benzothiazole
- 7-((p-(Dimethylamino)phenyl)azo)isoquinoline
- 73943-41-6Phenol,2-fluoro-6-methoxy-
- 73948-18-2Benzenesulfonylchloride, 4-pentyl-
- 73953-89-61H-1,2,3-Triazole-4,5-dicarboxylicacid, 1-(phenylmethyl)-
- 73953-98-7Tropane-8-propionamide, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yloxy), oxime, di(hydrogen maleate)
- 73956-15-7Ethanethioamide,2,2-diethoxy-
- 73956-17-94-Thiazolecarboxylicacid, 2-formyl-, ethyl ester
- 73957-66-1Pyrazolo[1,5-a]pyridine-3-carboxaldehyde
- 73957-87-6Vancomycin,22-O-(3-amino-2,3,6-trideoxy-a-L-ribo-hexopyranosyl)-3-(3-chloro-4-hydroxyphenyl)-3-de(2-amino-2-oxoethyl)-10-dechloro-3''-demethyl-49-de[4-methyl-2-(methylamino)-1-oxopentyl]-49-[(2R)-[4-[(6-deoxy-a-L-mannopyranosyl)oxy]phenyl](methylamino)acetyl]-7-O-a-D-mannopyranosyl-, (3''R,4''R)-(9CI)
- 739-58-2Benzenamine,4-(diphenylphosphino)-N,N-dimethyl-
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one |
EINECS | 1806241-263-5 |
| CAS No. | 73942-87-7 | Density | 1.167 g/cm3 |
| PSA | 47.56000 | LogP | 1.67560 |
| Solubility | N/A | Melting Point |
244.0 to 248.0 °C |
| Formula | C12H13NO3 | Boiling Point | 455.8 °C at 760 mmHg |
| Molecular Weight | 219.24 | Flash Point | 229.5 °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
7,8-Dimethoxy-1,3-dihydro-2H-benzazepin-2-one;2H-3-benzazepin-2-one, 1,3-dihydro-7,8-dimethoxy-;7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one;7,8-Dimethoxy-1,3-dihydro-2H-benzazepin-2-one; |
Article Data | 18 |
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one Synthetic route
- 73942-87-7
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
| Conditions | Yield |
|---|---|
| With trifluoroacetic acid for 8h; Reflux; | 97% |
- 73954-34-4
N-(2,2-dimethoxy-ethyl)-3,4-dimethoxyphenylacetamide
- 73942-87-7
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
| Conditions | Yield |
|---|---|
| With hydrogenchloride; acetic acid In water at 25℃; for 17h; | 77.5% |
| With hydrogenchloride; acetic acid for 17h; Ambient temperature; | 75% |
| With hydrogenchloride; acetic acid In water at 20℃; for 8h; | 61.4% |
- 93-40-3
(3,4-Dimethoxyphenyl)acetic acid
- 73942-87-7
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: 81 percent / thionyl chloride / CH2Cl2 / 1 h / Heating 2: triethylamine / CH2Cl2 / 1 h / Ambient temperature 3: 75 percent / glacial acetic acid, conc. HCl / 17 h / Ambient temperature View Scheme | |
| Multi-step reaction with 2 steps 1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol 2: hydrogenchloride; acetic acid / water View Scheme | |
| Multi-step reaction with 2 steps 1: toluene / 30 h / Reflux 2: hydrogenchloride; sulfuric acid / water / 4 h / 25 - 30 °C / Reflux View Scheme | |
| Multi-step reaction with 3 steps 1: thionyl chloride / dichloromethane 2: triethylamine / dichloromethane 3: hydrogenchloride; acetic acid View Scheme | |
| Multi-step reaction with 2 steps 1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / N,N-dimethyl-formamide / 20 °C / Inert atmosphere 2: phosphorus pentaoxide / methanesulfonic acid / 20 °C / Inert atmosphere View Scheme |
- 10313-60-7
3,4-dimethoxyphenylacetyl chloride
- 73942-87-7
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: triethylamine / CH2Cl2 / 1 h / Ambient temperature 2: 75 percent / glacial acetic acid, conc. HCl / 17 h / Ambient temperature View Scheme | |
| Multi-step reaction with 2 steps 1: triethylamine / dichloromethane 2: hydrogenchloride; acetic acid View Scheme |
- 73942-87-7
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1.1: lithium triethylborohydride / tetrahydrofuran / 1.5 h / -78 °C 1.2: -78 - 20 °C 2.1: trifluoroacetic acid / 8 h / Reflux View Scheme |
- 85175-49-1
7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepine-2,4-dione
- 73942-87-7
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1.1: potassium carbonate; potassium iodide / acetonitrile / 27.5 h / 80 °C 2.1: lithium triethylborohydride / tetrahydrofuran / 1.5 h / -78 °C 2.2: -78 - 20 °C 3.1: trifluoroacetic acid / 8 h / Reflux View Scheme |
- 73942-87-7
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
- 293732-19-1
(4,5-dimethoxy-2-iodophenyl)methyl bromide
- 1104967-37-4
3-(2-iodo-4,5-dimethoxybenzyl)-7,8-dimethoxy-1,3-dihydrobenzo[d]azepin-2-one
| Conditions | Yield |
|---|---|
| Stage #1: 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one With potassium tert-butylate In N,N-dimethyl-formamide at 0℃; for 0.5h; Stage #2: (4,5-dimethoxy-2-iodophenyl)methyl bromide In N,N-dimethyl-formamide at 20℃; for 2h; | 98% |
- 6974-77-2
1-bromo-3-chloro-2-methyl propane
- 73942-87-7
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
- 85176-88-1
1-(7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-on-3-yl)-2-methyl-3-chloro-propane
| Conditions | Yield |
|---|---|
| 97.5% | |
| With potassium tert-butylate 1.) DMSO, RT, 30 min, 2.) RT, 30 min; Multistep reaction; |
- 73942-87-7
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
- 106-89-8
epichlorohydrin
- 85176-49-4
1-(7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-2-on-3-yl)-2,3-epoxy-propane
| Conditions | Yield |
|---|---|
| 94.5% |
- 73942-87-7
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one
- 109-70-6
1,3-chlorobromopropane
- 85175-59-3
3-(3-chloropropyl)-1,3-dihydro-7,8-dimethoxy-2H-3-benzazepine-2-one
| Conditions | Yield |
|---|---|
| Stage #1: 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one With potassium tert-butylate In dimethyl sulfoxide at 25 - 30℃; for 0.5h; Stage #2: 1.3-chlorobromopropane In dimethyl sulfoxide at 15 - 20℃; for 0.5h; Reagent/catalyst; Time; Temperature; Concentration; | 89% |
| 87.3% | |
| Stage #1: 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one With sodium hydride In N,N-dimethyl-formamide for 0.5h; Stage #2: 1.3-chlorobromopropane In N,N-dimethyl-formamide at 20℃; for 10.5h; | 66.5% |
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one Chemical Properties
Molecular Structure of 2H-3-Benzazepin-2-one,1,3-dihydro-7,8-dimethoxy- (CAS NO.73942-87-7):
.png)
Empirical Formula: C12H13NO3
Molecular Weight: 219.2365
H bond acceptors: 4
H bond donors: 1
Freely Rotating Bonds: 2
Polar Surface Area: 38.77 Å2
Index of Refraction: 1.546
Molar Refractivity: 59.47 cm3
Molar Volume: 187.8 cm3
Surface Tension: 39.4 dyne/cm
Density: 1.167 g/cm3
Flash Point: 229.5 °C
Enthalpy of Vaporization: 71.56 kJ/mol
Boiling Point: 455.8 °C at 760 mmHg
Vapour Pressure: 1.7E-08 mmHg at 25°C
7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one Specification
2H-3-Benzazepin-2-one,1,3-dihydro-7,8-dimethoxy- , with CAS number of 73942-87-7, can be called 1,3-Dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one ; 7,8-dimethoxy-1, 3-dihydro-2H-benzo[d] azepin-2-one ; 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one .
What can I do for you?
Get Best Price
