The Synthetase, acetylcoenzyme A, with the CAS registry number 9012-31-1, is also known as Acetate thiokinase. Its EINECS number is 232-729-7. Its EC number is 6.2.1.1. It is an enzyme involved in metabolism of carbon sugars. It is in the ligase class of enzymes, meaning that it catalyzes the formation of a new chemical bond between two large molecules. While Acetyl-CoA synthetase's activity is usually associated with metabolic pathways, the enzyme also participates in gene expression. In yeast, Acetyl-CoA synthetase delivers Acetyl-CoA to histone acetyltransferases for histone acetylation. Without correct acetylation, DNA cannot condense into chromatin properly, which inevitably results in transcriptional errors. Its storage temperature of -20 °C.