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Name	Azatadine maleate	EINECS	223-615-8
CAS No.	3978-86-7	Density	N/A
PSA	165.33000	LogP	3.06920
Solubility	N/A	Melting Point	152-154°
Formula	C₂₀H₂₂N₂^.2(C₄H₄O₄)	Boiling Point	450.1 °C at 760 mmHg
Molecular Weight	522.60	Flash Point	226 °C
Transport Information	N/A	Appearance	Powder
Safety		Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	6,11-dihydro-11-(1-methylpiperidin-4-ylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine dimaleate;6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine maleate (1:2);Optimine (TN);Azatadinum [INN-Latin];Azatadine maleate (USP);Azatadine maleate [USAN];Azatadina [INN-Spanish];5H-Benzo[5,6]cyclohepta[1,2-b]pyridine,6,11- dihydro-11-(1-methyl-4-piperidinylidene)-,(2Z)-2-butenedioate (1:2);

Azatadine maleate Chemical Properties

Product Name: Azatadine maleate (200 mg)
Synonyms: 11H-benzo(5,6)cyclohepta(1,2-b)pyridine,5,6-dihydro-11-(1-methyl-4-piperidylid ; 6,11-Dihydro-11-(1-methyl-4-piperidylidene)5H-benzo(5,6)cyclohepta(1,2-b)pyr ; Azatadinedimaleate ; Azatadinemaleate ; Idinedimaleate ; Idulian ; Optimine ; SCH10649
CAS NO: 3978-86-7
Molecular Formula: C₂₈H₃₀N₂O₈
Molecular Weight: 522.5464
Molecular Structure:
EINECS: 223-615-8
Mol File: 3978-86-7.mol
Flash Point: 226 °C
Enthalpy of Vaporization: 70.89 kJ/mol
Boiling Point: 450.1 °C at 760 mmHg
Vapour Pressure: 2.71E-08 mmHg at 25°C
Appearance: 6,11-Dihydro-11-(1-methyl-4-piperidylidene)5H-benzo(5,6)cyclohepta(1,2-b)pyr (CAS NO. 3978-86-7) is white or beige powder, odorless.

Azatadine maleate Uses

1. 6,11-Dihydro-11-(1-methyl-4-piperidylidene)5H-benzo(5,6)cyclohepta(1,2-b)pyr (CAS NO. 3978-86-7) is anti-allergic drug .
2. 6,11-Dihydro-11-(1-methyl-4-piperidylidene)5H-benzo(5,6)cyclohepta(1,2-b)pyr (CAS NO. 3978-86-7) is release resistance agent of allergy media.

Azatadine maleate Toxicity Data With Reference

1.	orl-rat LD50:440 mg/kg	TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),185.
2.	ipr-rat LD50:166 mg/kg	JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 1 (1975),173.
3.	scu-rat LD50:1000 mg/kg	JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 1 (1975),173.
4.	orl-mus LD50:184 mg/kg	JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 1 (1975),173.
5.	ipr-mus LD50:105 mg/kg	JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 1 (1975),173.
6.	scu-mus LD50:178 mg/kg	JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 1 (1975),173.
7.	scu-mus LDLo:50 mg/kg	JZKEDZ Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 1 (1975),79.

Azatadine maleate Safety Profile

Poison by ingestion, subcutaneous, and intraperitoneal routes. An antihistamine. When heated to decomposition it emits toxic fumes of NO_x.

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