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Boc-(R)-3-Amino-4-(4-trifluoromethylphenyl)butyric acid

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Name

Boc-(R)-3-Amino-4-(4-trifluoromethylphenyl)butyric acid

EINECS N/A
CAS No. 269726-77-4 Density 1.246 g/cm3
PSA 75.63000 LogP 4.00680
Solubility N/A Melting Point N/A
Formula C16H20F3NO4 Boiling Point 449.739 °C at 760 mmHg
Molecular Weight 347.33 Flash Point 225.794 °C
Transport Information N/A Appearance N/A
Safety 22-24/25 Risk Codes N/A
Molecular Structure Molecular Structure of 269726-77-4 (Boc-(R)-3-Amino-4-(4-trifluoromethyl-phenyl)-butyric acid) Hazard Symbols N/A
Synonyms

Benzenebutanoic acid, b-[[(1,1-dimethylethoxy)carbonyl]amino]-4-(trifluoromethyl)-,(bR)-;(R)-3-(Boc-amino)-4-[4-(trifluoromethyl)phenyl]butyric acid;Boc-4-(trifluoromethyl)-D-β-homophenylalanine;

Article Data 1

Boc-(R)-3-Amino-4-(4-trifluoromethylphenyl)butyric acid Specification

The Boc-(R)-3-Amino-4-(4-trifluoromethyl-phenyl)-butyric acid, with the CAS registry number 269726-77-4, is also known as (R)-Boc-4-(trifluoromethyl)-β-Homophe-OH. It belongs to the product categories of 3-Amino-4-phenylbutanoic Acid Analogs; B-Amino. This chemical's molecular formula is C16H20F3NO4 and molecular weight is 347.33. What's more, its systematic name is (3R)-3-[(tert-butoxycarbonyl)amino]-4-[4-(trifluoromethyl)phenyl]butanoic acid. It is irritant. You should not breathe dust. When using it, you should avoid contacting with skin and eyes. 

Physical properties of Boc-(R)-3-Amino-4-(4-trifluoromethyl-phenyl)-butyric acid are: (1)ACD/LogP: 3.75; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.47; (4)ACD/LogD (pH 7.4): 0.69; (5)ACD/BCF (pH 5.5): 21.64; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 135.44; (8)ACD/KOC (pH 7.4): 2.26; (9)#H bond acceptors: 5; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 7; (12)Polar Surface Area: 55.84 Å2; (13)Index of Refraction: 1.486; (14)Molar Refractivity: 80.07 cm3; (15)Molar Volume: 278.6 cm3; (16)Surface Tension: 36.8 dyne/cm; (17)Density: 1.246 g/cm3; (18)Flash Point: 225.8 °C; (19)Enthalpy of Vaporization: 74.66 kJ/mol; (20)Boiling Point: 449.7 °C at 760 mmHg; (21)Vapour Pressure: 7.1E-09 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES: FC(F)(F)c1ccc(cc1)C[C@@H](NC(=O)OC(C)(C)C)CC(=O)O
(2)InChI: InChI=1S/C16H20F3NO4/c1-15(2,3)24-14(23)20-12(9-13(21)22)8-10-4-6-11(7-5-10)16(17,18)19/h4-7,12H,8-9H2,1-3H3,(H,20,23)(H,21,22)/t12-/m1/s1
(3)InChIKey: UKFKHDUXBBWVHB-GFCCVEGCSA-N

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