Basic Information | Post buying leads | Suppliers |
Name |
Butethamine hydrochloride |
EINECS | N/A |
CAS No. | 553-68-4 | Density | 1.067g/cm3 |
PSA | N/A | LogP | N/A |
Solubility | N/A | Melting Point |
192-196° |
Formula | C13H20N2O2•ClH | Boiling Point | 383.7°Cat760mmHg |
Molecular Weight | 272.775 | Flash Point | 185.9°C |
Transport Information | N/A | Appearance | N/A |
Safety | A poison by intraperitoneal, intravenous, and subcutaneous routes. Used in veterinary medicine as local anesthetic. When heated to decomposition it emits very toxic fumes of Cl− and NOx. | Risk Codes | N/A |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
N/A |
Product Name: Butethamine hydrochloride
CAS Registry Number: 553-68-4
IUPAC Name: 2-(2-methylpropylamino)ethyl 4-aminobenzoate hydrochloride
Molecular Weight: 272.77104 [g/mol]
Molecular Formula: C13H21ClN2O2
H-Bond Donor: 3
H-Bond Acceptor: 4
Surface Tension: 41.6 dyne/cm
Density: 1.067 g/cm3
Flash Point: 185.9 °C
Enthalpy of Vaporization: 63.23 kJ/mol
Boiling Point: 383.7 °C at 760 mmHg
Vapour Pressure: 4.3E-06 mmHg at 25°C
Classification Code: Drug / Therapeutic Agent
Following is the molecular structure of Butethamine hydrochloride (CAS NO.553-68-4) is:
Butethamine hydrochloride (CAS NO.553-68-4) can be used in veterinary medicine as local anesthetic.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LDLo | subcutaneous | 215mg/kg (215mg/kg) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 62, Pg. 69, 1938. |
mouse | LD50 | intraperitoneal | 169mg/kg (169mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 115, Pg. 483, 1958. |
mouse | LD50 | intravenous | 36mg/kg (36mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: EXCITEMENT | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 115, Pg. 483, 1958. |
mouse | LD50 | subcutaneous | 449mg/kg (449mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Anesthesiology. Vol. 3, Pg. 398, 1942. |
rabbit | LDLo | intravenous | 30mg/kg (30mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 62, Pg. 69, 1938. |
rat | LD50 | intraperitoneal | 182mg/kg (182mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Anesthesiology. Vol. 3, Pg. 398, 1942. |
rat | LD50 | intravenous | 28mg/kg (28mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Anesthesiology. Vol. 3, Pg. 398, 1942. |
A poison by intraperitoneal, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
Butethamine hydrochloride , its cas register number is 553-68-4. It also can be called 2-(Isobutylamino)ethyl p-aminobenzoate hydrochloride ; 2-Isobutylaminoethanol hydrochloric acid salt, p-aminobenzoic acid ester ; Benzoic acid, p-amino-, 2-(isobutylamino)ethyl ester, hydrochloride ; Butethamine HCl ; Ibylcaine hydrochloride ; Monocaine hydrochloride ; NSC 10821 ; UNII-0M63DKI91K ; p-Aminobenzoic acid 2-(isobutylamino)ethyl ester hydrochloride ; p-Aminobenzoic acid ester of 2-isobutylaminoethanol ; hydrochloric acid salt ; Ethanol, 2-((2-methylpropyl)amino)-, 4-aminobenzoate
(ester), monohydrochloride (9CI) ; Ethanol, 2-(isobutylamino)-, p-aminobenzoate (ester), monohydrochloride .