cas 100369-95-7, 2-(4-METHOXY-PHENYL)-3-METHYL-MORPHOLINE | Articles data ｜lookchem

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100369-95-7

Articles about 100369-95-7Total 3 be found

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CINNOLINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS
The present invention is directed to certain cinnoline compounds of formula (I) that are PDE10 inhibitors, pharmaceutical compositions containing such compounds and process for preparing such compounds. The invention is also directed to methods of treating diseases treatable by modulation of PDE10 enzyme, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
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Page/Page column 49-50

(2010/11/28)

CINNOLINE AND QUINAZOLINE DERIVATES AS PHOSPHODIESTERASE 10 INHIBITORS
The present invention is directed to cinnoline and quinazoline compounds of formula (I) that are PDE10 inhibitors, pharmaceutical compounds containing the same and processes for preparing the same. The invention is also directed to methods of treating diseases mediated by PDE10 enzyme such as obesity, non-insulin dependent diabetes, schizophrenia or bipolar disorder, obsessive-compulsive disorder, and the like.
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Page/Page column 53

(2010/11/28)

4-AMINOMORPHOLINES.
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KALM
p. 427 - 433
(2007/10/04)

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Chemical Properties

Boiling Point: 327.4±37.0 °C at 760 mmHg
Flash Point:132.1±16.0 °C
Density: 1.0±0.1 g/cm³
Storage Temp.:2-8°C
PSA: 30.49000
LogP: 2.07340

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