- Multicomponent Cascade Synthesis of Biaryl-Based Chalcones in Pure Water and in an Aqueous Micellar Environment
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The challenging multicomponent cascade synthesis of biaryl-based chalcones was carried out in pure water and in an aqueous micellar system. The first step of the protocol was a simple Pd-catalysed, ligand-free, and aerobic Suzuki–Miyaura reaction in aqueous medium. This proved to be extremely efficient for the coupling of aryl and heteroaryl bromides with different arylboronic acids. Subsequently, the resulting intermediates underwent an in-situ aldol condensation reaction to give biaryl(hetero)chalcones in good to excellent yields. When the protocol was applied to highly lipophilic or less reactive reagents, micellar catalysis was required for good results. To achieve this, we successfully used a new surfactant obtained from renewable resources that we recently designed. Furthermore, using this additive, the catalytic system can be repeatedly recycled without significant loss of activity.
- Armenise, Nicola,Malferrari, Danilo,Ricciardulli, Sara,Galletti, Paola,Tagliavini, Emilio
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supporting information
p. 3177 - 3185
(2016/07/19)
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- 2-PYRROLIDONE DERIVATIVES FUNCTIONALIZED WITH AN ESTER, ACID OR AMIDE RADICAL, COSMETIC COMPOSITION COMPRISING THEM AND USE THEREOF FOR CONDITIONING KERATIN MATERIALS
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The invention relates to the use of compounds derived from 2-pyrrolidone functionalized in position 4 with an ester, carboxylic acid or amide radical, for cosmetically treating keratin materials, especially for conditioning keratin materials, and in particular in terms of the disentangling, straightening, combability and manageability of human keratin fibres such as the hair. The invention also relates to novel cationic monopyrrolidone derivatives and to a cosmetic composition comprising them. Besides the suppleness of the keratin fibre, the compounds of formula (I) as defined previously also make it possible to improve the disentangling, straightening, combability and manageability of the head of hair; the shaping of the head of hair is easier, and the hair has a very pleasant, fluid feel.
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Page/Page column 29-30
(2012/01/04)
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