- TRICYCLIC COMPOUND AS CRTH2 INHIBITOR
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Provided are a tricyclic compound as shown in formula (I) as a CRTH2 inhibitor, or a pharmaceutically acceptable salt, a tautomer, a stereoisomer or a solvate thereof, and the use thereof in treating diseases related to CRTH2 receptors.
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Paragraph 0208; 0209; 0243; 0244
(2019/06/07)
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- INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR
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The present application discloses an indole as represented by formula (I) used as a CRTH2 inhibitor, and a pharmaceutically acceptable salt or tautomer of the indole, and an application of same in treating a disease related to a CRTH2 receptor.
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Paragraph 0203; 0205; 0233-0234
(2019/06/07)
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- Indole derivatives with CRTH2 inhibitor activity
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The invention discloses indole derivatives having CRTH2 inhibitor activity and shown as formula (I) in the description or pharmaceutically acceptable salts of the indole derivatives and an applicationof the indole derivatives to treatment of CRTH2 recepto
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Paragraph 0107; 0110; 0111; 0131; 0132; 0133
(2018/05/16)
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- CYCLOADDITION REACTIONS OF 2-VINYLTHIOPHEN
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Cycloaddition reactions between 2-vinylthiophen and the dienophiles maleic anhydride, dimethyl acetylenedicarboxylate, methyl propiolate, and methyl acrylate, are reported.Products include simple benzotiophen carboxylates (6, 13, 17) and reduced derivatives (3, 4, 18).The acetylenic dienophiles also gave a dihydrobenzthienyl-acrylate (16) or -fumarate (11), and the dithienylcyclohexene esters (7) and (14).
- Abarca, Belen,Ballesteros, Rafael,Enriquez, Emilio,Jones, Gurnos
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p. 2435 - 2440
(2007/10/02)
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