Synthesis of 5-bromomethylisoxazoles and their reactions with secondary amines
Treating R-3-chloro-4-bromo-2-buten-1-ones with hydroxylamine hydrochloride afforded 3-alkyl(aryl, furyl)-5-bromomethylisoxazoles. By reaction of the latter with secondary amines new previously unknown aminoisoxazoles were synthesized. 2005 Pleiades Publi
Aliev
p. 1192 - 1195
(2007/10/03)
Regioisomeric 5(3)-aminomethyl-3(5)-phenylisoxazoles: Synthesis, spectroscopic discrimination, and muscarinic activity
The regioselective synthesis of isomeric 5(3)-aminomethyl-3(5)-phenyl isoxazoles using different methods is described. Spectroscopic data, especially mass spectrometric fragmentation, were used to identify and characterize the regioisomers. The muscarinic
Dannhardt,Lambrecht,Laufer,Mutschler,Schweiger
p. 437 - 443
(2007/10/02)
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