Synthesis and evaluation of bakuchiol derivatives as potential anticancer agents
A series of bakuchiol derivatives were synthesized and evaluated for their anti-proliferative and the inhibitory activities on SMMC7721 cell line migration using PX-478 as a positive control. The results showed (S,E)-4-(7-methoxy-3,7-dimethyl-3-vinyloct-1
Novel bisstyryl derivatives of bakuchiol: Targeting oral cavity pathogens
Novel bisstyryl derivatives of bakuchiol using Heck coupling reaction as the key step were synthesized and screened against a panel of six oral cavity pathogens for their antimicrobial activity. Four compounds (9-12) showed two to fourfold and four to eig
Mallepally V. Reddy,Niranjan Thota,Payare L. Sangwan,Pankaj Malhotra,Furqan Ali,Inshad A. Khan,Swapandeep S. Chimni,Koul, Surrinder
experimental part
p. 3125 - 3134
(2010/09/03)
Synthesis and structure-immunosuppressive activity relationships of bakuchiol and its derivatives
A series of derivatives of bakuchiol were synthesized and tested in vitro for their cytotoxicity, and inhibition of T cell proliferation and B cell proliferation. The data obtained provided preliminary structure-activity relationships of the compounds as immunosuppressive activity.