New glutamic and aspartic derivatives with potent CCK-antagonistic activity
New derivatives of aspartic and glutamic acid were synthesized and evaluated in vitro and in vivo for anti-CCK activity on the guinea pig gallbladder. The anti-CCK activity of some 4-benzamido-glutaramic acid derivatives was a hundred times greater than that of proglutamide, the model compound, and they have been selected for further studies.
Makovec,Chiste,Bani,et al.
p. 9 - 20
(2007/10/02)
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