Efficient synthesis of 3-arylaminopyrroline-2-ones by the tandem reaction of anilines and β,γ-unsaturated α-ketoesters
A concise and efficient synthetic approach to 3-arylaminopyrroline-2-ones from anilines and β,γ-unsaturated α-ketoesters in boiling dichloromethane has been developed. This protocol possesses many advantages such as short reaction time, high isolated yiel
1-Butyl-1-methylpyrrolidinium hydrogen sulfate-promoted preparation of 1,5-diaryl-3-(arylamino)-1H-pyrrol-2(5H)-one derivatives
A convenient preparative approach for synthesis of various 1,5-diaryl-3-(arylamino)-1H-pyrrol-2(5H)-ones promoted by 1-butyl-1- methylpyrrolidinium hydrogen sulfate is developed which involves cyclocondensation of aldehydes with amines and ethyl pyruvate under ambient conditions. Graphical abstract: A convenient preparative approach for synthesis of various 1,5-diaryl-3-(arylamino)-1H-pyrrol-2(5H)-ones promoted by 1-butyl-1-methylpyrrolidinium hydrogen sulfate is developed which involves cyclocondensation of aldehydes with amines and ethyl pyruvate under ambient conditions.[Figure not available: see fulltext.]
Ghashang, Majid
p. 2187 - 2195
(2013/06/26)
Recyclable fluorous organocatalysts promoted three-component reactions of pyruvate, aldehyde and amine at room temperature
A new fluorous imine carbothioate has been prepared as an organocatalyst for the synthesis of pyrrol-2-ones via the cyclo-condensation reaction of aldehydes, amines, and pyruvate at room temperature. The fluorous catalyst can be easily recovered from the reaction mixture by simple fluorous solid-phase extraction (F-SPE) and used for next run reaction without further purification.
Qian, Jin-Long,Yi, Wen-Bin,Cai, Chun
supporting information
p. 7100 - 7102
(2013/12/04)
More Articles about upstream products of 102750-04-9