- A phosphoric acid ester [...] synthesis method of disodium salt
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The present invention provides a pterostilbene phosphate disodium salt synthesis method, wherein an aprotic solvent is adopted to dissolve pterostilbene, a dialkoxyl phosphoryl halide is adopted as a phosphorylation regent, acylation is performed under catalysis effects of an acid removing agent and 4-dimethylaminopyridine to obtain pterostilbene-alkoxyl-phosphate ester, and hydrolysis, salt formation and crystallization are performed to obtain the pterostilbene phosphate disodium salt. The method has characteristics of mild reaction conditions, short reaction time, no requirement of purification of the phosphorylation intermediate, simple process, high yield, good product quality and low energy consumption, and is suitable for industrial production.
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Paragraph 0031-0032
(2017/03/08)
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- Synthesis and Biological Evaluation of 3,5-Dimethoxystilbene Analogs
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In our continuing effort to discover natural product-based pest management agents, derivatives of 3,5-dimethoxystilbene were synthesized yielding 27 new and six known compounds. Compounds 11 and 12 showed strong Aedes aegypti larvicidal activity (LC5
- Weng, Jian-Quan,Ali, Abbas,Estep, Alden,Becnel, James,Meyer, Susan L. F.,Wedge, David E.,Jacob, Melissa,Rimando, Agnes M.
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p. 1165 - 1177
(2016/09/28)
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- PREVENTION AND TREATMENT OF COLON CANCER
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Stilbene compounds for the prevention and treatment of colon cancer or colon inflammation and methods of using same are provided.
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Page/Page column 27-28
(2008/12/06)
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- Design, synthesis, biological evaluation and docking studies of pterostilbene analogs inside PPARα
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Pterostilbene, a naturally occurring analog of resveratrol, has previously shown PPARα activation in H4IIEC3 cells and was found to decrease cholesterol levels in animals. In this study, analogs of pterostilbene were synthesized and their ability to activ
- Mizuno, Cassia S.,Ma, Guoyi,Khan, Shabana,Patny, Akshay,Avery, Mitchell A.,Rimando, Agnes M.
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p. 3800 - 3808
(2008/09/21)
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