Inhibition of neuronal nitric oxide synthase by 4-amino pteridine derivatives: Structure-activity relationship of antagonists of (6R)-5,6,7,8- tetrahydrobiopterin cofactor
The family of nitric oxide synthases (NOS) catalyzes the conversion of L-arginine to L-citrulline and nitric oxide (NO), an important cellular messenger molecule which has been implicated in the pathophysiology of septic shock and inflammatory and neurode
Fr?hlich, Lothar G.,Kotsonis, Peter,Traub, Hermann,Taghavi-Moghadam, Shahriyar,Al-Masoudi, Najim,Hofmann, Heinrich,Strobel, Hartmut,Matter, Hans,Pfleiderer, Wolfgang,Schmidt, Harald H. H. W.
p. 4108 - 4121
(2007/10/03)
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