- Synthesis and oxidation reactions of a user- and eco-friendly hypervalent iodine reagent
-
Allylic and benzylic alcohols are cleanly oxidized to the corresponding carbonyl compounds in water or water-THF mixtures using a water-soluble derivative of o-iodoxybenzoic acid. A mechanism involving single electron transfer steps is proposed for this facile and eco-friendly oxidation protocol.
- Thottumkara, Arun P,Vinod, Thottumkara K
-
-
Read Online
- 4'-O-SUBSTITUTED ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME
-
Provided are 4'-O substituted isoindoline compounds, and pharmaceutically acceptable salts, solvates, clathrates, stereoisomers, and prodrugs thereof. Methods of use, and pharmaceutical compositions of these compounds are disclosed.
- -
-
-
- Isoindole-imide compounds and compositions comprising and methods of using the same
-
This invention relates to isoindole-imide compounds, and pharmaceutically acceptable salts, solvates, stereoisomers, and prodrugs thereof. Methods of use, and pharmaceutical compositions of these compounds are disclosed.
- -
-
Page/Page column 66
(2010/11/26)
-
- User- and eco-friendly hypervalent iodine reagent and method of synthesis
-
The present invention is a user- and eco-friendly hypervalent iodine reagent (mIBX) capable of selectively oxidizing allylic and benzylic alcohols in water and other eco-friendly solvents and having generally the following structure: 1Allylic and benzylic alcohols are cleanly oxidized to the corresponding carbonyl compounds in water or water-THF mixtures, or other mixtures, using a water-soluble o-iodoxybenzoic acid derivative of the present invention.
- -
-
Page 2; Sheet 1
(2010/02/05)
-