High potency dipeptide sweeteners. 1. L-aspartyl-D-phenylglycine esters
Twenty esters of L-aspartyl-D-phenylglycine, as well as two substituted analogues, an o-fluoro and a p-hydroxyphenylglycine ester, were prepared. The L-aspartyl-D-phenylglycine (-)-α- and (+)-β-fenchyl esters had the highest sweetness potency at 1200 and 3700 times that of sucrose, respectively. The high potency of these sweeteners is surprising as the phenyl group occupies a position previously believed to accommodate only much smaller groups.
Janusz,Gardklik,Young,Burkes,Stoll,Estelle,Riley
p. 1052 - 1061
(2007/10/02)
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