- Synthesis method of 2-(5-fluoro-2-nitrophenoxy)acetate compounds
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The invention relates to the field of pesticide chemical industry, and concretely relates to a synthesis method of 2-(5-fluoro-2-nitrophenoxy)acetate compounds. The method is characterized in that a compound shown as a formula (I) and a compound shown as a formula (II) react under the action of a catalyst to obtain the target products; the catalyst is at least one of sodium iodide and potassium iodide; and in the formulas, R1 is sodium or potassium, and R2 is a C1-C6 alkyl group or a benzyl group. According to the synthesis process, the byproduct potassium chloride generated after the reaction can be effectively separated through simple filtration, so that resource utilization of the byproduct potassium chloride is realized. In addition, the solvent can be recycled by means of evaporating and removing the solvent, so resource waste is greatly reduced, cost is saved, and the environment is protected.
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Paragraph 0063-0066; 0072
(2021/07/01)
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- Production process of flumioxazin herbicide
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The invention discloses a production process of a flumioxazin herbicide. The process is characterized by comprising the following steps: S1, synthesizing 2-nitro-5-fluorophenol; S2, synthesizing ethyl 2-(5-fluoro-2-nitrophenoxy) acetate; S3, synthesizing 7-fluoro-2H-1, 4-benzoxazine-3 (4H)-ketone; S4, synthesizing 7-fluoro-6-nitro-2H-1, 4-benzoxazine-3 (4H)-ketone; S5, synthesizing 7-fluoro-6-amino-2H-1, 4-benzoxazine-3 (4H)-ketone; S6, synthesizing 7-fluoro-6-(3, 4, 5, 6-tetrahydro)phthalimido-1, 4-benzoxazine-3 (4H) ketone; and S7, synthesizing the flumioxazin. The method has the advantages of low raw material price, few byproducts and light pollution.
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- Cycloalkane-pyrimidinedione compound as well as preparation method and application and pesticide herbicide thereof (by machine translation)
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The invention relates to the field, discloses a cycloalkane-pyrimidinedione compound and a preparation method and application and a pesticide herbicide, and the compound has the structure shown in the formula (I). The cycloalkane pyrimidine diketone compo
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Paragraph 0102-0104
(2019/09/14)
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- Design, Herbicidal Activity, and QSAR Analysis of Cycloalka[ d]quinazoline-2,4-dione-Benzoxazinones as Protoporphyrinogen IX Oxidase Inhibitors
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In continuation of our search for potent protoporphyrinogen IX oxidase (PPO, EC 1.3.3.4) inhibitors, we designed and synthesized a series of novel herbicidal cycloalka[d]quinazoline-2,4-dione-benzoxazinones. The bioassay results of these synthesized compo
- Wang, Da-Wei,Zhang, Rui-Bo,Ismail, Ismail,Xue, Zhi-Yuan,Liang, Lu,Yu, Shu-Yi,Wen, Xin,Xi, Zhen
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p. 9254 - 9264
(2019/08/26)
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- Pyridine pyrimidine diketone containing benzoxazine ketone compound as well as preparation method and application thereof and herbicide composition
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The invention relates to the field of herbicides, and discloses a pyridine pyrimidine diketone containing benzoxazine ketone compound as well as a preparation method and application thereof and a herbicide composition. The structure of the benzoxazine ket
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Paragraph 0138; 0140; 0141
(2018/11/22)
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- Synthesis and Herbicidal Activity of Pyrido[2,3-d]pyrimidine-2,4-dione-Benzoxazinone Hybrids as Protoporphyrinogen Oxidase Inhibitors
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To search for new protoporphyrinogen oxidase (PPO, EC 1.3.3.4) inhibitors with improved bioactivity, a series of novel pyrido[2,3-d]pyrimidine-2,4-dione-benzoxazinone hybrids, 9-13, were designed and synthesized. Several compounds with improved tobacco PP
- Wang, Da-Wei,Li, Qian,Wen, Kai,Ismail, Ismail,Liu, Dan-Dan,Niu, Cong-Wei,Wen, Xin,Yang, Guang-Fu,Xi, Zhen
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p. 5278 - 5286
(2017/07/12)
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- PROCESS FOR PREPARATION OF DERIVATIVES OF TETRAHYDROPHTHALIMIDE
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The present disclosure provides a process for preparation of a compound of formula 1, or isomers or its derivatives thereof, which show a high herbicidal activity against wide variety of weeds. (I) wherein R1 is a C3-C4 al
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Paragraph 00064
(2014/08/20)
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- TRICYCLIC COMPOUNDS AS TEC KINASE INHIBITORS
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The present invention is directed to tricyclic compounds of formula (I) as Tec kinase inhibitors, in particular ITK (interleukin-2 inducible tyrosine kinase) inhibitors. Also provided herein are processes for preparing compounds described herein, intermed
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Page/Page column 47
(2013/11/05)
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- NOVEL COMPOUNDS
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The invention relates to tricyclic derivatives, and their use in treating diseases and conditions mediated by antagonism of the mGluR5 receptor, in particular substance related disorders. In addition, the invention relates to compositions containing the derivatives and processes for their preparation.
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Page/Page column 40
(2011/12/14)
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- New herbicide models from benzoxazinones: Aromatic ring functionalization effects
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The utility of benzoxazinones and some of their synthetic derivatives in the search for new leads for herbicide model development has been widely discussed. As the benzoxazinone skeleton contains three different potential areas for functionalization (C-2,
- Macias, Francisco A.,De Siqueira, Joao M.,Chinchilla, Nuria,Marin, David,Varela, Rosa M.,Molinillo, Jose M. G.
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p. 9843 - 9851
(2008/02/04)
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- Herbicidal tricyclic heterocycles
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Compounds of Formula I having herbicidal utility are disclosed: STR1 wherein Q, R1, R2, V, m and p are defined in the text, including compositions containing such compounds, and a method for controlling weeds employing such compounds.
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- SUBSTITUTED-OPTIONALLY HYDROGENATED ISOQUINOLINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL METHOD OF USE
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The invention concerns a heterocyclene derivative of the formula I wherein Ar1 is optionally substituted phenyl, naphthyl or a 9- or 10-membered bicyclic heterocyclic moiety; A1 is a direct link to X1 or (1-3C)alkylene; X1 is oxy, thio, sulphinyl, sulphonyl or imino; Ar2 is optionally substituted 5-membered heterocyclene moiety; R1 is (1-4C)alkyl, (3-4C)alkenyl or (3-4C)alkynyl; and R2 and R3 together form a group of the formula -A2-X2-A3- which, together with the carbon atom to which A2 and A3 are attached, defines a ring having 5 to 7 ring atoms, wherein each of A2 and A3 is (1-3C)alkylene and X2 is oxy, thio, sulphinyl or sulphonyl; or a pharmaceutically-acceptable salt thereof. The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase
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- BENZOXAZINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENES
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The invention concerns a bicyclic heterocyclic compound of the formula I wherein Q is an optionally substituted 10-membered bicyclic heterocyclic moiety containing 1 or 2 N's and a further O or S heteroatom; A1 is a direct link to X1 or (1-3C)alkylene; X1 is oxy, thio, sulphinyl, sulphonyl or imino; Ar is optionally substituted phenylene or pyridylene; R1 is (1-4C)alkyl, (3-4C)alkenyl or (3-4C)alkynyl; and R2 and R3 together form a group of the formula -A2-X2-A3- which, together with the carbon atom to which A2 and A3 are attached, defines a ring having 5 to 7 ring atoms, wherein each of A2 and A3 is (1-3C)alkylene and X2 is oxy, thio, sulphinyl or sulphonyl; or a pharmaceutically-acceptable salt thereof. The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase
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- Herbicidally active benzoxazines
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Novel benzoxazines of the formula (I) STR1 wherein Q represents STR2 X represents hydrogen or fluorine; and R represents alkyl, alkenyl, alkynyl, cyclopropylmethyl, cyanoalkyl, alkoxyalkyl, or alkylthioalkyl; the use of the new compounds as herbicides, an
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- Tetrazolinone herbicides
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Herbicidal compounds of the formula STR1 in which R1 is H, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl, alkoxyalkyl, alkoxyalkoxyalkyl, alkylsulfonyl, aralkyl, alkylthioalkyl, hydroxy or alkoxy; R2 and R3
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