- Synthesis of new derivatives of 10H-benzo[b]pyridazino[3,4-e][1,4]thiazines
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New 10H-benzo[b]pyridazino[3,4-e][1,4]thiazines were prepared and evaluated for inhibitory activity against soybean 15-lipoxygenase enzyme. These compounds were synthesized by the sequential treatment of 4-bromo-3,6-dichloropyridazine with 2-aminothiophenol and a secondary amine with the subsequent heterocyclization in the presence of sodium amide.
- Arghiani, Zahra,Seyedi, Seyed Mohammad,Bakavoli, Mehdi,Nikpour, Mohsen
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p. 215 - 218
(2015/08/24)
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- DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES
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Bicyclic nitrogen containing compounds and their use as antibacterials.
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Page/Page column 38-39
(2008/06/13)
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- PYRROLO-QUINOXALINONE DERIVATIVES AS ANTIBACTERIALS
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Tricyclic nitrogen containing compounds of the following Formula (I) and their use as antibacterials.
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Page/Page column 30
(2008/06/13)
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- Triazolo-pyridazine derivatives as ligands for GABA receptors
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1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing an optionally substituted cycloalkyl, phenyl or heteroaryl substituent at the 3-position, a substituted alkoxy moiety at the 6-position, an optionally substituted N-linked nitrogen-containing aliphat
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- Triazolo-pyridazine derivatives as ligands for GABA receptors
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1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing a fluoro-substituted phenyl ring at the 3-position and a heteroaryl-alkoxy moiety at the 6-position, are selective ligands for GABAAreceptors, in particular having high affinity for the α2
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- Triazolo-pyridazine derivatives as ligands for GABA receptors
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1,2,4-triazolo[4,3-b]pyridazine derivatives, represented by wherein Z represents cyclobutyl or pyrrolidin-1-yl, are selective ligands for GABAAreceptors, in particular having high affinity for the α2 and/or α3 subunit thereof, are useful in the
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- Substituted triazolo-pyridazine derivatives as ligands for GABA receptors
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Substituted triazolo-pyridazine derivative compounds represented by wherein the variables are disclosed herein are selective ligands for GABA-A receptors, particularly for the α2 and/or α3 subunits.
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- Triazolo-pyridazine derivatives as ligands for GABA receptors
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1,2,4-triazolo[4,3-b]pyridazine derivatives, represented by wherein Z represents cyclobutyl, 1-methylcyclopentyl or pyrrolidin-1-yl, are selective ligands for GABAAreceptors, in particular having high affinity for the α2 and/or α3 subunit there
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- Triazolo-pyridazine derivatives as ligands for GABA receptors
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1,2,4-triazolo[4,3-b]pyridazine derivatives, represented by wherein Z represents an optionally substituted tetrahydropyridinyl substituent, are selective ligands for GABAAreceptors, in particular having high affinity for the α2 and/or α3 subuni
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