A convenient procedure for the preparation of sulfonamidoureas using triphosgene
An efficient method for the preparation of sulfonamidourea using triphosgene in organic solvents is reported. Sulfonylhydrazides and acetylsulfanilylhydrazide were transformed into the corresponding intermediates using triphosgene in 1,4-dioxane/water or tetrahydrofuran as solvents. These intermediates were converted in situ into symmetrical and unsymmetrical sulfonamidoureas in high yields and shorter periods of time related to previous methods.