Synthesis and hydroxyapatite binding activity of bisphosphonate-statin conjugates
To develop a methodology for delivering anabolic agents statins to bone, a bone targeting bisphosphonate was used as a carrier of drugs. Four statin-bisphosphonate conjugates were synthesized and examined for their bone mineral affinity in vitro by hydrox
Xu, Guangyu,Zuo, Gaolei,Zhong, Shihua,Zhang, Wei
experimental part
p. 419 - 423
(2010/04/23)
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