- New 30-noroleanane triterpenoid saponins from Holboellia coriacea Diels
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Three new 30-noroleanane triterpenoid saponins, akebonoic acid 28-O-β-D-glucopyranosyl-(1″→6′)-β-D-glucopyranosyl ester (1), akebonoic acid 28-O-(6″-O-caffeoyl)-β-D-glucopyranosyl-(1″→6′)-β-D-glucopyranosyl ester (Holboelliside A, 2) and 3β,20α,24-trihydroxy-29-norolean-12-en-28-oic acid 3-O-(6′-O-caffeoyl)-β-D-glucopyranoside (Holboelliside B, 3) were isolated from the stems of Holboellia coriacea Diels, together with five known compounds, eupteleasaponin VIII (4), 3α-akebonoic acid (5), quinatic acid (6), 3β-hydroxy-30-norhederagenin (7) and quinatoside A (8). The structures of these compounds were determined on the basis of spectral and chemical evidence. Compounds 1-5 were evaluated for their inhibitory activity against three human tumors HepG2, HCT116 and SGC-7901 cell lines in vitro.
- Ding, Wenbing,Li, Ye,Li, Guanhua,He, Hualiang,Li, Zhiwen,Li, Youzhi
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- Bidesmoside triterpenoid glycosides from Stauntonia chinensis and relationship to anti-inflammation
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Ten triterpenoid glycosides, yemuoside YM26-35 (1-9 and 12), were isolated from a traditional Chinese medicine known as "Ye Mu Gua" (Stauntonia chinensis DC.) along with two known ones, kalopanax saponin C (10) and sieboldianoside A (11). Their
- Gao, Hao,Zhao, Feng,Chen, Guo-Dong,Chen, Shao-Dan,Yu, Yang,Yao, Zhi-Hong,Lau, Brad W.C.,Wang, Zhao,Li, Jin,Yao, Xin-Sheng
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experimental part
p. 795 - 806
(2010/05/17)
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- TRITERPENOID SAPONINS OF Guaiacum officinale
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Three new nortriterpenoidal saponins, guaianins A, 1, A1, 2, and B, 3, have been isolated from the stem bark of Guaiacum officinale(Zygophyllaceae).The structure of these saponins have been established on the basis of spectral evidence as 3-O--30-norolea-12,20(29)-dien-28-oic acid, 3-O--30-norolea-12,20(29)-dien-28-oic acid and 3-O-(1-3)-α-L-arabinopyranosyl-30-norolea-12,20(29)-dien-28-O-β-D-glucopyranosyl ester, respectively.
- Ahmad, Viqar Uddin,Bano, Shaheen,Fatima, Iqbal,Bano, Nasreen,Riccio, Raffaele,Minale, Luigi
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- Saponins from Leaves of Acanthopanax senticosus HARMS., Ciwujia; Structures of Ciwujianosides B, C1, C2, C3, C4, D1, D2 and E
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Eleven triterpenoid saponins were isolated from the leaves of a Chinese folk medicine, Acanthopanax senticosus (RUPR. et MAXIM) HARMS.Of these compounds, three were identified as known saponins.The structures of eight new saponins named ciwujianosides B (1), C1, (2), C2 (3), C3 (4), C4 (5), D1 (6), D2 (7), and E (8) were elucidated to be as follows: (1), 3-O-α-rhamnopyranosyl-(1->2)-β-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (2), 3-O-α-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (3), 3-O-α-rhamnopyranosyl-(1->2)-α-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (4), 3-O-α-arabinopyranosyl oleanolic acid 28-O-α-rhamnopyranosyl-(1->4)-β-glucopyranosyl(1->6)-β-glucopyranosyl ester; (5), 3-O-α-rhamnopyranosyl-(1->2)-α-arabinopyranosyl oleanolic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (6), 3-O-α-arabinopyranosyl oleanolic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-β-glucopyranosyl(1->6)-β-glucopyranosyl ester; (7), 3-O-α-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-b-glucopyranosyl-30-norolean-12,20(29)-dien-28-oic acid 28-O-α-rhamnopyranosyl-(1->4)-6-O-acetyl-β-glucopyranosyl-(1->6)-β-glucopyranosyl ester; (8), 3-O-α-rhamnopyranosyl-(1->2)-α-arabinopyranosyl-30-norolean-12,20(29)-dien-28-oic acid.Keywords - Acanthopanax senticosus; Araliaceae; saponin; Chinese folk medicine; ciwujianoside; oleanolic acid glycoside; noroleanolic acid glycoside; 30-norolean-12,20(29)-dien-28-oic acid; ciwujia
- Shao, Chun-Jie,Kasai, Ryoji,Xu, Jing-Da,Tanaka, Osamu
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p. 601 - 608
(2007/10/02)
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