Development of hydroxamate-based histone deacetylase inhibitors of bis-substituted aromatic amides with antitumor activities
Previously, we designed and synthesized a series of bis-substituted aromatic amide-based histone deacetylase (HDAC) inhibitors. In this study, we report the replacement of a bromine atom by different amides on the phenyl ring of the CAP region. Representa
Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists
Compositions and methods for treatment of a urinary tract dysfunction by administering to a subject in need of such treatment a pharmaceutical composition including a delta opioid receptor agonist in an amount effective to reduce the effects of the urinar
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(2008/06/13)
Method of treating sexual dysfunctions with delta opioid receptor agonist compounds
Compositions and methods for treatment of sexual dysfunctions by administering to a subject a pharmaceutical composition comprising a delta opioid receptor agonist in an amount effective to delay the onset of ejaculation in the subject during sexual stimulation.
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(2008/06/13)
Method of treating depression with delta receptor agonist compounds
Compositions and methods for treatment of depression or other affective mood disorders or pathological mental and/or emotional states, by administration to a subject suffering or susceptible to same, of therapeutically effective delta receptor agonist com
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(2008/06/13)
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