A NOVEL AND EFFICIENT SYNTHESIS OF 5-SUBSTITUTED AND 5,6-DISUBSTITUTED 4-METHYLCOUMARINS USING ORGANOCERIUM(III) REAGENTS
Addition of organocerium(III) reagent, Cl2CeCH2COOt-Bu, to the appropriate ortho-methoxymethoxyacetophenones followed by acid treatment gives 5-substituted and 5,6-disubstituted 4-methylcoumarins in excellent yields.