This invention relates to the use of quinazolinediones for the modulation, notably the inhibition of the activity of tankyrases (TNKS1 and TNKS2). Suitably, the present invention relates to the use of quinazolinediones in the treatment of cancer, fibrosis and other hyperproliferative diseases through this mechanism.
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Page/Page column 44; 45
(2014/01/07)
Chinazolincarbonsaeuren; 3,4-Dihydro-4-oxo-(chinazolin oder 1,2,3-benzotriazin)-3-methyl-cyclohexancarbonsaeuren
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Suesse, Manfred,Johne, Siegfried
p. 250 - 251
(2007/10/02)
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