- Modulation of the inositol 1,4,5-trisphosphate receptor by inositol phosphates
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The mode of recognition at the binding site of the Ins(1,4,5)P3 receptor was assessed by examining the structure-activity relationships of different Ca2+-mobilizing inositol phosphates.
- Lu, Pei-Jung,Chen, Ching-Shih
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p. 325 - 328
(2007/10/03)
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- An efficient chemoenzymic access to optically active myo-inositol polyphosphates
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The 1,4,5-tris-, 1,3,4-tris-, and 1,3,4,5-tetrakis-phosphates of 1D-myo-inositol have been prepared in their enantiomerically pure forms from the two enantiomers of 1,2:5,6-di-O-cyclohexylidene-myo-inositol. A facile enzymic preparation is also described
- Gou,Liu,Chen
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- THE TOTAL SYNTHESIS OF myo-INOSITOL POLYPHOSPHATES
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Total synthesis of the individual enentiomers of myo-inositol 4-phosphate (15), myo-inositol 1,4-biphosphate (2) and myo-inositol 1,4,5-triphosphate (1), together with syntheses of racemic myo-inositol 1,3,4-triphosphate (4) and myo-inositol 2,4,5-triphos
- Vacca, Joseph P.,deSolms, S. Jane,Huff, Joel R.,Billington, David C.,Baker, Raymond,et al.
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p. 5679 - 5702
(2007/10/02)
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- AN EFFICIENT SYNTHESIS OF OPTICALLY ACTIVE D-MYO-INOSITOL 1,4,5-TRIPHOSPHATE
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An effective synthesis of D-myo-inositol 1,4,5-triphosphate was developed using a chiral inositide precursor which can be prepared via a facile enzymatic or chemical method.
- Liu, Yeuk-Chuen,Chen, Ching-Shih
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p. 1617 - 1620
(2007/10/02)
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- Enantiospecific Synthesis of D-myo-Inositol 1,4,5-Trisphosphate from (-)-Quinic Acid
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A versatile, enentiospecific approach to functionalized cyclitols from (-)-quinic acid is illustrated by a synthesis of D-myo-inositol 1,4,5-trisphosphate, the calcium-mobilizing intracellular second messenger of the phosphatidylinositol cycle.
- Falck, J. R.,Yadagiri, Pendri
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p. 5851 - 5852
(2007/10/02)
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