Synthesis and antibacterial activity of new 2-substituted penems. II
A series of new penems (4 ~ 17), having a bicyclic imidazole moiety as the C-2 substituent, has been synthesized. The antimicrobial activity of these compounds and their susceptibility to renal dehydropeptidase-1 (DHP-1) are elucidated, and their structure-activity relationships are discussed.
Nishi,Higashi,Soga,Takemura,Sato
p. 357 - 369
(2007/10/02)
Mercapto-bicycloheterocyclics useful as intermediates for penem derivatives
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(2008/06/13)
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