Novel synthetic luteolin analogue-caused sensitization of tumor necrosis factor-α-induced apoptosis in human tumor cells
Studies on the sensitization, by novel alkynyl luteolin analogues, of TNF-α-induced apoptosis in HeLa and HepG2 cells revealed that LA-12 showed better sensitizing effects on TNF-α-induced cell death than luteolin, suggesting great potential for alkynyl luteolin analogues in cancer therapy.