- Synthesis of 5-substituted resorcinol derivatives via cross-coupling reactions
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Suzuki and Stille cross-coupling reactions were utilized in the synthesis of 5-substituted 1,3-dimethoxybenzerie and 5-substituted resorcinol derivatives. The substituted resorcinol derivatives were obtained in only three steps from inexpensive reagents. 1,3-Dimethoxybenzoic acid and 1-chloro-3,5-dimethoxybenzene were transformed into 1-iodo-, 1-bromo-, 1-trimethyltin-3,5-dimethoxybenzene and 3,5-dimethoxyphenyl boronic acid. 5-Allyl-1,3-dimethoxybenzene and 3,5-dimethoxybiphenyl derivatives were obtained via cross coupling reactions under mild conditions. HI, BBr3 and AlI3 were used to demethylate these dimethoxybenzenes into their resorcinol derivatives.
- Dol, Georg C.,Kamer, Paul C. J.,Van Leeuwen, Piet W. N. M.
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- Synthesis and study of new paramagnetic resveratrol analogues
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New resveratrol analogues containing five- and six-membered nitroxides and isoindoline nitroxides were synthesized. These new compounds were compared to resveratrol based on their ABTS radical scavenging ability as well on their capacity to suppress infla
- Kálai, Tamás,Borza, Erzsébet,Antus, Csenge,Radnai, Balázs,Gulyás-Fekete, Gergely,Fehér, Andrea,Sümegi, Balázs,Hideg, Kálmán
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experimental part
p. 7311 - 7317
(2012/01/03)
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