cas 109244-58-8, DIHYDRORHODAMINE 123 | Articles data ｜lookchem

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109244-58-8

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Synthesis and Biological Studies of Iodinated (127/125I) Derivatives of Rhodamine 123
Rhodamine 123, a mitochondrial stain that preferentially accumulates in certain cancer cells, has been reduced and iodinated by using NaI in the presence of N-chlorosuccinimide.The various mono-, di-, and triiodo derivatives have been isolated and charact
Kinsey, Berma M.,Kassis, Amin I.,Fayad, Fahed,Layne, Warren W.,Adelstein, S. James
p. 1757 - 1761
(1987)
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A significant improvement of the efficacy of radical oxidant probes by the kinetic isotope effect
A breath of fresh air: The rate of aerial oxidation of dihydroethidium and hydrocyanine radical oxidant probes can be selectively reduced by deuteration (see picture). The reaction rate between the deuterated compounds and the superoxide radical was reduced by a much smaller factor because of mechanistic differences between the two reactions.
Kundu, Kousik,Knight, Sarah F.,Lee, Seungjun,Taylor, W. Robert,Murthy, Niren
supporting information; experimental part
p. 6134 - 6138
(2010/12/20)

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Chemical Properties

Melting Point: 163–165℃
Boiling Point: 526.877 °C at 760 mmHg
Flash Point:222.398 °C
Density: 1.313g/cm³
Solubility:DMSO: >5mg/mL
Storage Temp.:−20°C
Vapor Pressure: 3.43E-11mmHg at 25°C
Refractive Index: 1.683
PKA: 4.70 ± 0.40, most basic, temperature: 25 °C
BRN: 5989965
PSA: 87.57000
LogP: 5.08590

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