- Sulfonamide derivative as well as preparation method and application thereof (by machine translation)
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The invention relates to a sulfonamide derivative and a preparation method and application thereof. At the same time α - glucosaccharase inhibitory activity of the synthesized compound is evaluated, and the SW480 result shows that the compound also has certain α - glucosaccharase inhibitory activity, and the compound has a wide prospect in the aspects of development and application of medicines for treating diabetes. (by machine translation)
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- Potent non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex
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Measles virus (MV) is one of the most infectious pathogens known. In spite of the existence of a vaccine, approximately 350000 deaths/year result from MV or associated complications. Antimeasles compounds could conceivably diminish these statistics and pr
- Sun, Aiming,Yoon, Jeong-Joong,Yin, Yan,Prussia, Andrew,Yang, Yutao,Min, Jaeki,Plemper, Richard K.,Snyder, James P.
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experimental part
p. 3731 - 3741
(2009/04/10)
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- BENZISOTHIAZOLE-1, 1-DIOXIDE ACTING AS ANTAGONISTS TO THE VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USES THEREOF
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Compounds having formula (I) or a pharmaceutically acceptable salt, prodrug, or salt of a prodrug thereof, wherein L, A, G, R1, R2 and R3 are as defined herein. These compounds are particularly useful in the treatment of pain, inflammatory hyperalgesia, and urinary dysfunctions, such as bladder overactivity and urinary incontinence.
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Page/Page column 24-25
(2008/06/13)
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