Synthesis and evaluation of benzothiazole-Based analogues as novel, potent, and selective fatty acid amide hydrolase inhibitors
High-throughput screening (HTS) identified benzothiazole analogue 3 as a potent fatty acid amide hydrolase (FAAH) inhibitor. Structure-activity relationship (SAR) studies indicated that the sulfonyl group, the piperidine ring and benzothiazole were the ke
Wang, Xueqing,Sarris, Katerina,Kage, Karen,Zhang, Di,Brown, Scott P.,Kolasa, Teodozyi,Surowy, Carol,El Kouhen, Odile F.,Muchmore, Steven W.,Brioni, Jorge D.,Stewart, Andrew O.
experimental part
p. 170 - 180
(2009/08/07)
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