- STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI
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The present invention relates to novel strobilurine type compounds I, processes for preparing these compounds, a use of compounds of the formula I and/or their agriculturally useful salts for controlling phytopathogenic fungi, to compositions comprising at least one such compound, to plant health applications, and to seeds coated with at least one such compound.
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Page/Page column 101; 102
(2015/01/07)
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- HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES
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Disclosed are compounds of Formula 1, including all stereoisomers, N oxides, and salts thereof, wherein Y is a 5-membered, fully or partially unsaturated heterocyclic ring containing 2-4 carbon atoms and 2-3 nitrogen atoms as ring members, the ring substi
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Page/Page column 39
(2011/06/16)
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- Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors
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A pyridazin-4-one fragment 4 (hCatS IC50 = 170 μM) discovered through Tethering was modeled into cathepsin S and predicted to overlap in S2 with the tetrahydropyridinepyrazole core of a previously disclosed series of CatS inhibitors. This fragment served as a template to design pyridazin-3-one 12 (hCatS IC50 = 430 nM), which also incorporates P3 and P5 binding elements. A crystal structure of 12 bound to Cys25Ser CatS led to the synthesis of the potent diazinone isomers 22 (hCatS IC50 = 60 nM) and 27 (hCatS IC50 = 40 nM).
- Ameriks, Michael K.,Bembenek, Scott D.,Burdett, Matthew T.,Choong, Ingrid C.,Edwards, James P.,Gebauer, Damara,Gu, Yin,Karlsson, Lars,Purkey, Hans E.,Staker, Bart L.,Sun, Siquan,Thurmond, Robin L.,Zhu, Jian
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scheme or table
p. 4060 - 4064
(2010/08/07)
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- ISOMERIC PURINONES AND 1H-IMIDAZOPYRIDINONES AS PKC-THETA INHIBITORS
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A chemical genus of purinones and 1H-imidazopyridinones, which are useful as PKCθ inhibitors, and their methods of use are disclosed. The genus is represented by the Formula (I).
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Page/Page column 39-40
(2009/06/27)
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