Discovery of 4H-thieno[3,2-b]pyrrole derivatives as potential anticancer agents
In this study, we describe the discovery of the 4H-thieno[3,2-b]pyrrole derivatives as an useful scaffold to obtain potent lead compounds for the treatment of colon cancer. We first started with the 4H-thieno[3,2-b]pyrrole derivatives which come from comp
Thienopyrrole derivative as well as preparation method and application thereof
A thienopyrrole derivative is named as 3-phenyl-N-(3-(trifluoromethyl) phenyl)-4H-thieno[3,2-b]pyrrole-5-formamide, the molecular formula of the thienopyrrole derivative is C20H13F3N2OS, and the molecular weight of the thienopyrrole derivative is 386.4. T
The present invention relates to certain compounds that function as inhibitors of bacterial metallo-beta-lactamases. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of a bacterial infection.
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Paragraph 00158
(2018/12/13)
HETEROCYCLIC AMIDE DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS
The invention relates to compounds of Formula (I) (or pharmaceutically acceptable salts thereof) as defined herein, pharmaceutical compositions thereof, and their use in manufactures and methods for modulating biological processes including antagonism of Prostaglandin EP4 receptor as a therapeutic treatment.
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Paragraph 0140; 0141
(2016/04/26)
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